Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. Published

    a, a´- trehalose 6,6´- dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying. / Christensen, Dennis; Kirby, Daniel; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Perrie, Yvonne; Nielsen, Hanne Mørck.

    In: Biochimica et Biophysica Acta - Biomembranes, Vol. 1778, No. 5, 2008, p. 1365-1373.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen. / Foged, Camilla; Ingvarsson, Pall Thor; Follmann, Frank; Christensen, Dennis; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2013, 2013, p. 41-43.

    Research output: Contribution to journalJournal articleResearch

  3. Published

    Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen. / Foged, Camilla; Ingvarsson, Pall Thor; Follmann, Frank; Christensen, Dennis; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2013, 2013, p. 41-43.

    Research output: Contribution to journalJournal articleResearch

  4. Published

    Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles. / Christophersen, P.; Vaghela, D.; Müllertz, Anette; Yang, Mingshi; Nielsen, Hanne Mørck; Mu, Huiling.

    2014. Abstract from 41st Controlled Release Society (CRS) Annual Meeting, Chicago, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  5. Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles. / Christophersen, P.; Vaghela, D.; Müllertz, Anette; Yang, Mingshi; Nielsen, Hanne Mørck; Mu, Huiling.

    2014. Abstract from 41st Controlled Release Society (CRS) Annual Meeting, Chicago, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  6. Published

    Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying. / Christensen, Dennis; Foged, Camilla; Rosenkrands, Ida; Nielsen, Hanne Mørck; Andersen, Peter; Agger, Else Marie.

    In: BBA General Subjects, Vol. 1768, No. 9, 2007, p. 2120-2129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Three-Dimensional Printing of Drug-Eluting Implants : Preparation of an Antimicrobial Polylactide Feedstock Material. / Water, Jorrit Jeroen; Bohr, Adam; Bøtker, Johan Peter; Aho, Johanna; Sandler, Niklas; Nielsen, Hanne Mørck; Rantanen, Jukka.

    In: Journal of Pharmaceutical Sciences, 15.01.2015, p. 1099–1107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models. / Ingvarsson, Pall Thor; Rasmussen, Ida Svahn; Viaene, Michelle; Irlik, Przemyslaw Jedrzej; Nielsen, Hanne Mørck; Foged, Camilla.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 87, No. 3, 08.2014, p. 480-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles. / García-Díaz, María; Birch, Ditlev; Wan, Feng; Nielsen, Hanne Mørck.

    In: Advanced Drug Delivery Reviews, Vol. 124, 01.2018, p. 107-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium. / Portero, Ana; Remuñán-López, Carmen; Nielsen, Hanne Mørck.

    In: Pharmaceutical Research, Vol. 19, No. 2, 2002, p. 169-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The impact of particle preparation methods and polymorphic stability of lipid excipients on protein distribution in microparticles. / Liu, Jingying; Christophersen, Philip C; Yang, Mingshi; Nielsen, Hanne M; Mu, Huiling.

    In: Drug Development and Industrial Pharmacy, Vol. 43, No. 12, 12.2017, p. 2032-2042.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues. / Bahnsen, Jesper Søborg; Franzyk, Henrik; Nielsen, Hanne Mørck.

    2012. Poster session presented at Zing Peptide Therapeutics Conference, 2012, Lanzarote, Spain.

    Research output: Contribution to conferencePosterResearch

  15. Published

    The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues. / Bahnsen, Jesper Søborg; Franzyk, Henrik; Nielsen, Hanne Mørck.

    2012. Poster session presented at Zing Peptide Therapeutics Conference, 2012, Lanzarote, Spain.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli. / Jahnsen, Rasmus D; Sandberg-Schaal, Anne; Vissing, Karina Juul; Nielsen, Hanne Mørck; Frimodt-Møller, Niels; Franzyk, Henrik.

    In: Journal of Medicinal Chemistry, Vol. 57, No. 7, 20.03.2014, p. 2864-2873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    TR146 cells grown on filters as a model of human buccal epithelium : III. Permeability enhancement by different pH values, different osmolality values, and bile salts. / Nielsen, Hanne Mørck; Rassing, M R.

    In: International Journal of Pharmaceutics, Vol. 185, No. 2, 1999, p. 215-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    TR146 cells grown on filters as a model of human buccal epithelium : IV. Permeability of water, mannitol, testosterone and beta-adrenoceptor antagonists. Comparison to human, monkey and porcine buccal mucosa. / Nielsen, H M; Rassing, M R; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 194, No. 2, 2000, p. 155-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    TR146 cells grown on filters as a model of human buccal epithelium : permeability of fluorescein isothiocyanate-labelled dextrans in the presence of sodium glycocholate. / Nielsen, Hanne Mørck; Verhoef, J C; Ponec, M; Rassing, M R.

    In: Journal of Controlled Release, Vol. 60, No. 2-3, 1999, p. 223-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    TR146 cells grown on filters as a model of human buccal epithelium : V. Enzyme activity of the TR146 cell culture model, human buccal epithelium and porcine buccal epithelium, and permeability of leu-enkephalin. / Mørck Nielsen, H; Rømer Rassing, M; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 200, No. 2, 2000, p. 261-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy. / Falkenberg, Emily; de Groot, Anne Marit; Sijts, Alice J A M; Thanki, Kaushik; Zeng, Xianghui; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Poster session presented at 10th European Workshop on Particulate Systems (EWPS), Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  22. Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices. / Steffensen, Søren Langer; Merete H., Vestergaard,; Jensen, Minna Grønning; Alm, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 94, 2015, p. 305-311.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices. / Steffensen, Søren Langer; Merete H., Vestergaard,; Jensen, Minna Grønning; Alm, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 94, 2015, p. 305-311.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro. / Zeng, Xianghui; de Groot, A. M.; Sijts, Alice; Blenke, E. O.; Colombo, Stefano; van Eden, W; Franzyk, Henrik; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Nanoscale, Vol. 7, No. 46, 2015, p. 19687-19698.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  26. Published

    Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  27. Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23-24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  28. Published

    Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23-24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    Structure of immune stimulating complex matrices and immune stimulating complexes in suspension determined by small-angle X-ray scattering. / Pedersen, Jan Skov; Oliveira, Cristiano Luis Pinto De; Madsen, Henriette Baun; Arleth, Lise; Manniche, Søren; Kirkby, Nicolai ; Nielsen, Hanne Mørck.

    In: Biophysical Journal, Vol. 102, No. 10, 2012, p. 2372-2380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation. / Bøgh, Marie; García-Díaz, María; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 94, No. Part A, 09.2015, p. 136–143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity. / Birch, Ditlev; Christensen, Malene Vinther; Stærk, Dan; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Biochemical Journal, Vol. 475, No. 10, 24.05.2018, p. 1773-1788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators. / Nordly, Pernille Juul; Madsen, Henriette Baun; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 6, No. 7, 2009, p. 1-16.

    Research output: Contribution to journalReviewResearch

  33. Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators. / Nordly, Pernille Juul; Madsen, Henriette Baun; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 6, No. 7, 2009, p. 1-16.

    Research output: Contribution to journalReviewResearch

  34. Published

    Stabilization of liposomes during drying. / Ingvarsson, Páll Þór; Yang, Mingshi; Nielsen, Hanne Mørck; Rantanen, Jukka Tapio; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 8, No. 3, 2011, p. 375-388.

    Research output: Contribution to journalReviewResearch

  35. Stabilization of liposomes during drying. / Ingvarsson, Páll Þór; Yang, Mingshi; Nielsen, Hanne Mørck; Rantanen, Jukka Tapio; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 8, No. 3, 2011, p. 375-388.

    Research output: Contribution to journalReviewResearch

  36. Published

    Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Solid-phase route to Fmoc-protected cationic amino acid building blocks. / Clausen, Jacob Dahlqvist; Linderoth, Lars; Nielsen, Hanne Mørck; Franzyk, Henrik.

    In: Amino Acids, Vol. 43, No. 4, 2012, p. 1633-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin. / Christophersen, Philip C; Vaghela, Dimple; Müllertz, Anette; Yang, Mingshi; Nielsen, Hanne M; Mu, Huiling.

    In: A A P S Journal, Vol. 16, No. 4, 07.2014, p. 875-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis. / Christophersen, Philip Carsten B; Zhang, L.; Yang, M; Nielsen, H Mørck; Müllertz, A; Mu, H.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 85, No. 3, part A, 02.08.2013, p. 473-480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation. / Christophersen, Philip Carsten; Zhang, Long; Müllertz, Anette; Nielsen, Hanne Mørck; Yang, Mingshi; Mu, Huiling.

    In: Pharmaceutical Research, Vol. 31, No. 9, 13.03.2014, p. 2420-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Soft hydrogels interpenetrating silicone – a polymer network for drug releasing medical devices. / Steffensen, Søren Langer; Merete H., Vestergaard,; Møller, Eva Horn; Jensen, Minna Grønning; Alm, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials, Vol. 104, No. 2, 2016, p. 402-410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Silicone embedded nanogels for prolonged resistance against biofilm formation. / Steffensen, Søren Langer; Vestergaard, M. H.; Jensen, Minna Grønning; Alm, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    2014. Poster session presented at Controlled Release Society Annual Meeting 2014, Chicago, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  44. Silicone embedded nanogels for prolonged resistance against biofilm formation. / Steffensen, Søren Langer; Vestergaard, M. H.; Jensen, Minna Grønning; Alm, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    2014. Poster session presented at Controlled Release Society Annual Meeting 2014, Chicago, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  45. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery : In vitro and in vivo evaluations of enteric coating and drug loading. / Li, Ping; Tan, Angel; Prestidge, Clive A; Nielsen, Hanne Mørck; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 477, No. 1-2, 30.12.2014, p. 390-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin. / Hyrup Møller, Laura; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Østergaard, Jesper; Stürup, Stefan; Gammelgaard, Bente.

    In: European Journal of Pharmaceutical Sciences, Vol. 67, 25.01.2015, p. 76-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2015. Poster session presented at Crossing Biological Barriers, Dresden, Germany.

    Research output: Contribution to conferencePosterResearchpeer-review

  48. Published

    Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2015. Poster session presented at Crossing Biological Barriers, Dresden, Germany.

    Research output: Contribution to conferencePosterResearchpeer-review

  49. Published

    Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators. / Baker, Kristin R; Jana, Bimal; Hansen, Anna Mette; Vissing, Karina Juul; Nielsen, Hanne Mørck; Franzyk, Henrik; Guardabassi, Luca.

    In: International Journal of Antimicrobial Agents, Vol. 53, 2019, p. 868-872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics. / Baker, Kristin R.; Jana, Bimal; Hansen, Anna Mette; Nielsen, Hanne Morck; Franzyk, Henrik; Guardabassi, Luca.

    In: Frontiers in Cellular and Infection Microbiology, Vol. 9, 02.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 1299091