Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  3. Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density. / Jensen, Linda Boye; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Rutherford, Sandra; Danani, Andrea; Nielsen, Hanne Mørck; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 416, 2011, p. 410-418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Petersson, K.

    In: Journal of Pharmacy and Pharmacology, 2010, p. 793-794.

    Research output: Contribution to journalConference abstract in journalResearch

  5. Published

    Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density. / Jensen, Linda Boye; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Rutherford, Sandra; Danani, Andrea; Nielsen, Hanne Mørck; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 416, 2011, p. 410-418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin. / Jensen, Linda Boye; Petersson, K.; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 79, No. 1, 2011, p. 68-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Petersson, K.

    In: Journal of Pharmacy and Pharmacology, 2010, p. 793-794.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  9. Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K.; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations. / Jensen, Linda Boye; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations. / Jensen, Linda Boye; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles. / Jensen, Louise B.; Magnusson, Emily; Gunnarsson, Linda; Vermehren, Charlotte; Nielsen, Hanne Mørck; Petersson, Karsten.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 53-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles. / Jensen, Louise B.; Magnusson, Emily; Gunnarsson, Linda; Vermehren, Charlotte; Nielsen, Hanne Mørck; Petersson, Karsten.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 53-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Kan nanopartikler bruges i behandlingen af hudsygdomme? / Jensen, Louise Bastholm; Knudsen, Nina Østergaard; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  15. Kan nanopartikler bruges i behandlingen af hudsygdomme? / Jensen, Louise Bastholm; Knudsen, Nina Østergaard; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  16. Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System. / Jing, Xiaona; Foged, Camilla; Martin-Bertelsen, Birte; Yaghmur, Anan; Knapp, Kolja Michael; Malmsten, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Molecular Pharmaceutics, Vol. 13, No. 6, 06.06.2016, p. 1739-1749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone : effects of hydrogen bonding and α-chirality in the β-peptoid residues. / Jing, Xiaona; Yang, Mingjun; Kasimova, Marina Robertovna; Malmsten, Martin; Franzyk, Henrik; Jørgensen, Lene; Foged, Camilla; Nielsen, Hanne Mørck.

    In: BBA General Subjects, Vol. 1818, No. 11, 2012, p. 2660-2668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group. / Jing, Xiaona; Simonsen, Anders Husted; Kasimova, Marina Robertovna; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23/24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  19. Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group. / Jing, Xiaona; Simonsen, Anders Husted; Kasimova, Marina Robertovna; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23/24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  20. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System. / Jing, Xiaona; Foged, Camilla; Martin-Bertelsen, Birte; Yaghmur, Anan; Knapp, Kolja Michael; Malmsten, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Molecular Pharmaceutics, Vol. 13, No. 6, 06.06.2016, p. 1739-1749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Cellular and intracellular distribution of recombinant activated factor VII in the rat liver. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik I.; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 103, No. 4, 2010, p. 860-862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver. / Johansen, Torben Seested; Appa, R. S.; Christensen, E. I.; Ioannou, Y. A.; Krogh, T. N.; Karpf, D. M.; Nielsen, Hanne Mørck.

    In: Thrombosis Research, Vol. 127, No. 4, 2011, p. 356-362.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver. / Johansen, Torben Seested; Appa, R. S.; Christensen, E. I.; Ioannou, Y. A.; Krogh, T. N.; Karpf, D. M.; Nielsen, Hanne Mørck.

    In: Thrombosis Research, Vol. 127, No. 4, 2011, p. 356-362.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cellular and intracellular distribution of recombinant activated factor VII in the rat liver. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik I.; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 103, No. 4, 2010, p. 860-862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  28. Published

    Issues in development of biodrug delivery systems. / Jørgensen, Lene; Frøkjær, Sven; Nielsen, Hanne Mørck.

    Biodrug delivery systems: fundamentals, applications and clinical development. ed. / Mariko Morishita; Kinam Park. New York : Informa Healthcare, 2010. p. 13-25.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    Biotechnology-based pharmaceuticals. / Jørgensen, Lene; Nielsen, Hanne Mørck; Frøkjær, Sven.

    Modern pharmaceutics: applications and advances. ed. / Alexander T. Florence; Juergen Siepmann. Vol. 2 5. ed. New York : Informa Healthcare, 2009. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  30. Published

    Issues in development of biodrug delivery systems. / Jørgensen, Lene; Frokjaer, Sven; Nielsen, Hanne Mørck.

    Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. CRC Press, 2016. p. 13-25.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Biotechnology-based pharmaceuticals. / Jørgensen, Lene; Nielsen, Hanne Mørck; Frøkjær, Sven.

    Modern pharmaceutics: applications and advances. ed. / Alexander T. Florence; Juergen Siepmann. Vol. 2 5. ed. New York : Informa Healthcare, 2009. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  32. Issues in development of biodrug delivery systems. / Jørgensen, Lene; Frøkjær, Sven; Nielsen, Hanne Mørck.

    Biodrug delivery systems: fundamentals, applications and clinical development. ed. / Mariko Morishita; Kinam Park. New York : Informa Healthcare, 2010. p. 13-25.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  33. Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  34. Published

    On the temperature dependence of complex formation between chitosan and proteins. / Kasimova, Marina Robertovna; Valázquez-Campoy, Adrián ; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 12, No. 7, 2011, p. 2534-2543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. On the temperature dependence of complex formation between chitosan and proteins. / Kasimova, Marina Robertovna; Valázquez-Campoy, Adrián; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 12, No. 7, 2011, p. 2534-2543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients : Challenges and Drug Delivery Approaches. / Klodzinska, Sylvia Natalie; Priemel, Petra Alexandra; Rades, Thomas; Mørck Nielsen, Hanne.

    In: International Journal of Molecular Sciences , Vol. 17, No. 10, 1688, 09.10.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach. / Klodzinska, Sylvia Natalie; Priemel, Petra Alexandra; Rades, Thomas; Nielsen, Hanne Mørck.

    In: Journal of Microbiological Methods, Vol. 144, 01.2018, p. 177-185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cellular effects and delivery propensity of penetratin is influenced by conjugation to parathyroid hormone fragment 1-34 in synergy with pH. / Kristensen, Mie; Nielsen, Line Hagner; Zor, Kinga; Boisen, Anja; Christensen, Malene Vinther; Berthelsen, Jens; Nielsen, Hanne Mørck.

    In: Bioconjugate Chemistry, Vol. 29, No. 2, 2018, p. 371-381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Parathyroid hormone coupled to cell-penetrating peptides for oral delivery. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  40. Published

    Peptide-enhanced oral delivery of therapeutic peptides and proteins. / Kristensen, Mie; Foged, Camilla; Berthelsen, Jens; Nielsen, Hanne Mørck.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 365-373.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published
  42. Published

    Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation. / Kristensen, Mie; de Groot, Anne Marit; Berthelsen, Jens; Franzyk, Henrik; Sijts, Alice; Nielsen, Hanne Mørck.

    In: Bioconjugate Chemistry, Vol. 26, 2015, p. 477-488.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation. / Kristensen, Mie; Franzyk, Henrik; Klausen, M. T.; Iversen, A; Bahnsen, Jesper Søborg; Skyggebjerg, R. B.; Foderà, Vito; Nielsen, Hanne Mørck.

    In: A A P S Journal, Vol. 17, No. 5, 2015, p. 1200-1209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cell-penetrating peptides as tools to enhance non-injectable delivery of biopharmaceuticals. / Kristensen, Mie; Nielsen, Hanne Mørck.

    In: Tissue Barriers, Vol. 4, No. 2, e1178369, 2016.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Characterization of PTH-CPP fusion peptides for oral delivery. / Kristensen, Mie; Berthelsen, Jens; Nielsen, Hanne Mørck.

    2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  46. Published

    Penetratin-mediated transepithelial insulin pemeation: Importance of complexation? / Kristensen, Mie; Foderà, Vito; Nielsen, Hanne Mørck.

    2015.

    Research output: Contribution to conferencePosterResearchpeer-review

  47. Published

    Parathyroid hormone coupled to cell-penetrating peptides for oral delivery. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  48. Published

    Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation. / Kristensen, Mie; Franzyk, Henrik; Klausen, M. T. ; Iversen, A; Bahnsen, Jesper Søborg; Skyggebjerg, R. B.; Foderà, Vito; Nielsen, Hanne Mørck.

    In: A A P S Journal, Vol. 17, No. 5, 2015, p. 1200-1209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2015. Poster session presented at Crossing Biological Barriers, Dresden, Germany.

    Research output: Contribution to conferencePosterResearchpeer-review

  50. Published

    Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos. / Kristensen, Mie; Birch, Ditlev; Mørck Nielsen, Hanne.

    In: International Journal of Molecular Sciences , Vol. 17, No. 2, 185, 30.01.2016, p. 1-17.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 1299091