Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  2. Published

    Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23-24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  4. Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius. / Damborg, Peter Panduro; Skindersø, Mette E; Hansen, Paul Robert; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Guardabassi, Luca.

    2012. Poster session presented at 13th Conference of the International Society for Veterinary Epidemiology and Economics (ISVEE XIII), Maastricht, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  5. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius. / Damborg, Peter Panduro; Skindersø, Mette E; Hansen, Paul Robert; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Guardabassi, Luca.

    2012. Poster session presented at 13th Conference of the International Society for Veterinary Epidemiology and Economics (ISVEE XIII), Maastricht, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  6. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate. / Eirheim, Heidi Ugelstad; Bundgaard, Christoffer; Nielsen, Hanne Mørck.

    In: Toxicology in Vitro, Vol. 18, No. 5, 2004, p. 649-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy. / Falkenberg, Emily; de Groot, Anne Marit; Sijts, Alice J A M; Thanki, Kaushik; Zeng, Xianghui; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Poster session presented at 10th European Workshop on Particulate Systems (EWPS), Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  8. Published

    Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen. / Foged, Camilla; Ingvarsson, Pall Thor; Follmann, Frank; Christensen, Dennis; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2013, 2013, p. 41-43.

    Research output: Contribution to journalJournal articleResearch

  11. Published

    Genetisk nanomedicin til behandling af leddegigt. / Foged, Camilla; Jensen, Linda Boye; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 12.2011, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  12. Published

    Cell-penetrating peptides for cytosolic delivery of biomacromolecules. / Foged, Camilla; Jing, Xiaona; Nielsen, Hanne Mørck.

    Organelle-specific pharmaceutical nanotechnology. ed. / Volkmar Weissig; Gerard G.M. D'Souza. Hoboken : Wiley, 2010. p. 403-432.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  13. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras : lessons for the design of new cell-penetrating peptides. / Foged, Camilla; Franzyk, Henrik; Bahrami, Shervin; Frøkjær, Sven; Jaroszewski, Jerzy Witold; Nielsen, Hanne Mørck; Olsen, Christian Adam.

    In: BBA General Subjects, Vol. 1778, No. 11, 2008, p. 2487-2495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen. / Foged, Camilla; Ingvarsson, Pall Thor; Follmann, Frank; Christensen, Dennis; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2013, 2013, p. 41-43.

    Research output: Contribution to journalJournal articleResearch

  16. Published

    Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA. / Foged, Camilla (Inventor); Franzyk, Henrik (Inventor); Zeng, Xianghui (Inventor); Nielsen, Hanne Mørck (Inventor); Thanki, Kaushik (Inventor).

    IPC No.: A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00. Patent No.: WO2017158093-A1. Mar 16, 2017.

    Research output: PatentResearch

  17. Published

    Cell-penetrating peptides for drug delivery across membrane barriers. / Foged, Camilla; Nielsen, Hanne Moerck.

    In: Expert Opinion on Drug Delivery, Vol. 5, No. 1, 2008, p. 105-17.

    Research output: Contribution to journalReviewResearch

  18. Published

    Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test. / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Internation Journal of Pharmaceutics, Vol. 331, No. 2, 2007, p. 160-166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Genetisk nanomedicin til behandling af leddegigt. / Foged, Camilla; Jensen, Linda Boye; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 12.2011, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  21. Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test. / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Internation Journal of Pharmaceutics, Vol. 331, No. 2, 2007, p. 160-166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Cell-penetrating peptides for cytosolic delivery of biomacromolecules. / Foged, Camilla; Jing, Xiaona; Nielsen, Hanne Mørck.

    Organelle-specific pharmaceutical nanotechnology. ed. / Volkmar Weissig; Gerard G.M. D'Souza. Hoboken : Wiley, 2010. p. 403-432.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  23. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids. / Garcia Diaz, Maria; Foged, Camilla; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 482, 2015, p. 84-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids. / Garcia Diaz, Maria; Foged, Camilla; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 482, 2015, p. 84-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles. / García-Díaz, María; Birch, Ditlev; Wan, Feng; Nielsen, Hanne Mørck.

    In: Advanced Drug Delivery Reviews, Vol. 124, 01.2018, p. 107-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Antimicrobial activity of GN peptides and their mode of action. / Godballe, Troels; Mojsoska, Biljana; Nielsen, Hanne M; Jenssen, Håvard.

    In: Biopolymers, Vol. 106, No. 2, 13.12.2015, p. 172–183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2014. Poster session presented at AMP 2014 - 4th International Symposium on Antimicrobial Peptides, LLorient, France.

    Research output: Contribution to conferencePosterResearchpeer-review

  28. Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2013. Poster session presented at ULLA Summerschool, London, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  29. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma. / Greco, Ines; Hummel, Bernard D.; Vasir, Jaspreet; Watts, Jeffrey L.; Koch, Jason ; Hansen, Johannes E.; Nielsen, Hanne Mørck; Damborg, Peter Panduro; Hansen, Paul Robert.

    In: Molecules, Vol. 23, No. 3, 630, 10.03.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2013. Poster session presented at ULLA Summerschool, London, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  31. AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2014. Poster session presented at AMP 2014 - 4th International Symposium on Antimicrobial Peptides, LLorient, France.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. Published

    Assessment of mucoadhesion using small deformation rheology revisited. / Harloff-Helleberg, Stine; Vissing, Karina Juul; Nielsen, Hanne Mørck.

    In: Nordic Rheology Society Annual Transactions, Vol. 25, 04.2017, p. 63.

    Research output: Contribution to journalConference articleResearchpeer-review

  33. Published

    Animal models for evaluation of oral delivery of biopharmaceuticals. / Harloff-Helleberg, Stine; Nielsen, Line Hagner; Nielsen, Hanne Mørck.

    In: Journal of Controlled Release, Vol. 268, 12.2017, p. 57-71.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals. / Harloff-Helleberg, Stine; Fliervoet, Lies A. L.; Fano, Mathias; Schmitt, Mechthild; Antopolski, Maxim; Urtti, Arto; Nielsen, Hanne Morck.

    In: Drug Delivery, Vol. 26, No. 1, 01.01.2019, p. 532-541.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction. / Hedegaard, Sofie Fogh; Derbas, Mohammed Sobhi; Lind, Tania Kjellerup; Kasimova, Marina Robertnova; Christensen, Malene Vinther; Michaelsen, Maria Høtoft; Campbell, Richard A; Jorgensen, Lene; Franzyk, Henrik; Cárdenas, Marité; Nielsen, Hanne Mørck.

    In: Scientific Reports, Vol. 8, No. 1, 6327, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin. / Hyrup Møller, Laura; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Østergaard, Jesper; Stürup, Stefan; Gammelgaard, Bente.

    In: European Journal of Pharmaceutical Sciences, Vol. 67, 25.01.2015, p. 76-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Designing CAF-adjuvanted dry powder vaccines : spray drying preserves the adjuvant activity of CAF01. / Ingvarsson, Pall Thor; Schmidt, Signe Tandrup; Christensen, Dennis; Larsen, Niels Bent; Hinrichs, Wouter Leonardus Joseph; Andersen, Peter; Rantanen, Jukka; Nielsen, Hanne Mørck; Yang, Mingshi; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 167, No. 3, 08.02.2013, p. 256-264.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models. / Ingvarsson, Pall Thor; Rasmussen, Ida Svahn; Viaene, Michelle; Irlik, Przemyslaw Jedrzej; Nielsen, Hanne Mørck; Foged, Camilla.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 87, No. 3, 08.2014, p. 480-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Engineering of an Inhalable DDA/TDB Liposomal Adjuvant : A Quality-by-Design Approach Towards Optimization of the Spray Drying Process. / Ingvarsson, Pall Thor; Yang, Mingshi; Mulvad, Helle; Nielsen, Hanne Mørck; Rantanen, Jukka; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 30, No. 11, 22.06.2013, p. 2772-2784.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Stabilization of liposomes during drying. / Ingvarsson, Páll Þór; Yang, Mingshi; Nielsen, Hanne Mørck; Rantanen, Jukka Tapio; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 8, No. 3, 2011, p. 375-388.

    Research output: Contribution to journalReviewResearch

  41. Published

    Stabilization of liposomes during drying. / Ingvarsson, Páll Þór; Yang, Mingshi; Nielsen, Hanne Mørck; Rantanen, Jukka Tapio; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 8, No. 3, 2011, p. 375-388.

    Research output: Contribution to journalReviewResearch

  42. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli. / Jahnsen, Rasmus D; Sandberg-Schaal, Anne; Vissing, Karina Juul; Nielsen, Hanne Mørck; Frimodt-Møller, Niels; Franzyk, Henrik.

    In: Journal of Medicinal Chemistry, Vol. 57, No. 7, 20.03.2014, p. 2864-2873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    End Group Modification : Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria. / Jahnsen, Rasmus O; Sandberg-Schaal, Anne; Frimodt-Møller, Niels; Nielsen, Hanne Mørck; Franzyk, Henrik.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 95, No. Part A, 23.01.2015, p. 40–46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. E-pub ahead of print

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model. / Jansen, Manon A A; Klausen, Lasse H; Thanki, Kaushik; Lyngsø, Jeppe; Skov Pedersen, Jan; Franzyk, Henrik; Nielsen, Hanne M; van Eden, Willem; Dong, Mingdong; Broere, Femke; Foged, Camilla; Zeng, Xianghui.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 11.06.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Molecular Characterization of the Interaction between siRNA and PAMAM G7 Dendrimers by SAXS, ITC, and Molecular Dynamics Simulations. / Jensen, Linda B.; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina R.; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne M.; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 12.2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin. / Jensen, Linda Boye; Petersson, K.; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 79, No. 1, 2011, p. 68-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1299091