Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. 2019
  2. Published

    Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators. / Baker, Kristin R; Jana, Bimal; Hansen, Anna Mette; Vissing, Karina Juul; Nielsen, Hanne Mørck; Franzyk, Henrik; Guardabassi, Luca.

    In: International Journal of Antimicrobial Agents, Vol. 53, 2019, p. 868-872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics. / Baker, Kristin R.; Jana, Bimal; Hansen, Anna Mette; Nielsen, Hanne Morck; Franzyk, Henrik; Guardabassi, Luca.

    In: Frontiers in Cellular and Infection Microbiology, Vol. 9, 02.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR. / Christensen, Malene Vinther; Kongstad, Kenneth Thermann; Sondergaard, Teis Esben; Stærk, Dan; Nielsen, Hanne Mørck; Franzyk, Henrik; Wimmer, Reinhard.

    In: Journal of Biomolecular N M R, Vol. 73, 2019, p. 167-182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model. / Jansen, Manon A A; Klausen, Lasse H; Thanki, Kaushik; Lyngsø, Jeppe; Skov Pedersen, Jan; Franzyk, Henrik; Nielsen, Hanne M; van Eden, Willem; Dong, Mingdong; Broere, Femke; Foged, Camilla; Zeng, Xianghui.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 11.06.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5. / Kłodzińska, Sylvia N.; Pletzer, Daniel; Rahanjam, Negin; Rades, Thomas; Hancock, Robert E.W.; Nielsen, Hanne M.

    In: Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 20, 102022, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement. / Malekkhaiat Häffner, Sara; Nyström, Lina; Browning, Kathryn L; Mörck Nielsen, Hanne; Strömstedt, Adam A; van der Plas, Mariena J A; Schmidtchen, Artur; Malmsten, Martin.

    In: A C S Applied Materials and Interfaces, Vol. 11, No. 17, 01.05.2019, p. 15389-15400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients. / Molchanova, Natalia; Wang, Hengzhuang; Hansen, Paul R; Høiby, Niels; Nielsen, Hanne M; Franzyk, Henrik.

    In: Frontiers in Microbiology, Vol. 10, 275, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement. / Rune Jørgensen, Jacob; Leth Jepsen, Morten; Hagner Nielsen, Line; Dufva, Martin; Mørck Nielsen, Hanne; Rades, Thomas; Boisen, Anja; Müllertz, Anette.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 143, 2019, p. 98-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers. / Stie, Mai Bay; Jones, Megan; Osholm Sørensen, Henning; Jacobsen, Jette; Chronakis, Ioannis S. ; Nielsen, Hanne Mørck.

    In: Carbohydrate Polymers, 01.07.2019, p. 253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration. / Thanki, Kaushik; van Eetvelde, Delphine; Geyer, Antonia; Fraire, Juan; Hendrix, Remi; Van Eygen, Hannelore; Putteman, Emma; Sami, Haider; de Souza Carvalho-Wodarz, Cristiane; Franzyk, Henrik; Nielsen, Hanne Mørck; Braeckmans, Kevin; Lehr, Claus-Michael; Ogris, Manfred; Foged, Camilla.

    In: Journal of controlled release : official journal of the Controlled Release Society, 06.08.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Impact of capacity-limited binding on recombinant factor VIII and von Willebrand factor pharmacokinetics in hemophilia A rats. / Vargas Christensen, Isabell; Loftager, Mette; Rode, Frederik; Mørck Nielsen, Hanne; Kreilgaard, Mads; Larsen, Malte Selch.

    In: Journal of Thrombosis and Haemostasis, Vol. 17, No. 6, 2019, p. 964-974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. E-pub ahead of print

    Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring. / Wan, Feng; Nylander, Tommy; Foged, Camilla; Yang, Mingshi; Baldursdottir, Stefania G; Nielsen, Hanne M.

    In: Journal of Colloid and Interface Science, Vol. 545, 01.03.2019, p. 162-171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2018
  15. Published

    Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin. / Birch, Ditlev; Christensen, Malene Vinther; Stærk, Dan; Franzyk, Henrik; Nielsen, Hanne Mørck.

    2018. Abstract from Controlled Release Society Annual Meeting & Exposition (CRS 2018), New York, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium. / Birch, Ditlev; Diedrichsen, Ragna G; Christophersen, Philip C; Mu, Huiling; Nielsen, Hanne M.

    In: European Journal of Pharmaceutical Sciences, Vol. 118, 06.2018, p. 144-153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity. / Birch, Ditlev; Christensen, Malene Vinther; Stærk, Dan; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Biochemical Journal, Vol. 475, No. 10, 24.05.2018, p. 1773-1788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles. / García-Díaz, María; Birch, Ditlev; Wan, Feng; Nielsen, Hanne Mørck.

    In: Advanced Drug Delivery Reviews, Vol. 124, 01.2018, p. 107-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma. / Greco, Ines; Hummel, Bernard D.; Vasir, Jaspreet; Watts, Jeffrey L.; Koch, Jason ; Hansen, Johannes E.; Nielsen, Hanne Mørck; Damborg, Peter Panduro; Hansen, Paul Robert.

    In: Molecules, Vol. 23, No. 3, 630, 10.03.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction. / Hedegaard, Sofie Fogh; Derbas, Mohammed Sobhi; Lind, Tania Kjellerup; Kasimova, Marina Robertnova; Christensen, Malene Vinther; Michaelsen, Maria Høtoft; Campbell, Richard A; Jorgensen, Lene; Franzyk, Henrik; Cárdenas, Marité; Nielsen, Hanne Mørck.

    In: Scientific Reports, Vol. 8, No. 1, 6327, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach. / Klodzinska, Sylvia Natalie; Priemel, Petra Alexandra; Rades, Thomas; Nielsen, Hanne Mørck.

    In: Journal of Microbiological Methods, Vol. 144, 01.2018, p. 177-185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cellular effects and delivery propensity of penetratin is influenced by conjugation to parathyroid hormone fragment 1-34 in synergy with pH. / Kristensen, Mie; Nielsen, Line Hagner; Zor, Kinga; Boisen, Anja; Christensen, Malene Vinther; Berthelsen, Jens; Nielsen, Hanne Mørck.

    In: Bioconjugate Chemistry, Vol. 29, No. 2, 2018, p. 371-381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic. / Kłodzińska, Sylvia Natalie; Molchanova, Natalia; Franzyk, Henrik; Hansen, Paul Robert; Damborg, Peter; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 128, 07.2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing. / Liu, Xiaoli; Nielsen, Line Hagner; Klodzinska, Sylvia Natalie; Nielsen, Hanne Mørck; Qu, Haiyan; Christensen, Lars Porskjær; Rantanen, Jukka; Yang, Mingshi.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 123, 02.2018, p. 42-49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Poly(ethylene carbonate)-containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages. / Priemel, Petra A.; Wang, Yingya; Bohr, Adam; Water, Jorrit J.; Yang, Mingshi; Nielsen, Hanne Morck.

    In: Journal of Pharmacy and Pharmacology, Vol. 70, No. 8, 08.2018, p. 1009-1021.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies. / Thanki, Kaushik; Thakur, Aneesh; de Groot, A. M.; Geyer, A.; Fraire, Juan; Falkenberg, Emily; Van Eygen, Hannelore; Putteman, Emma; Van Bijnen, Djai C. J.; Zeng, Xianghui; Sami, H.; Gehrig, S. ; Justesen, Sarah; Franzyk, Henrik; Broere, Femke; van Eden, Willem; Sijts, Alice J A M; Ogris, M.; Nielsen, Hanne Mørck; Braeckmans, Kevin; Foged, Camilla.

    2018. Abstract from Controlled Release Society Annual Meeting & Exposition (CRS 2018), New York, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  27. Published

    Lipid shell-enveloped polymeric nanoparticles with high integrity of lipid shells improve mucus penetration and interaction with cystic fibrosis-related bacterial biofilms. / Wan, Feng; Nylander, Tommy; Klodzinska, Sylvia Natalie; Foged, Camilla; Yang, Mingshi; Baldursdottir, Stefania G; Mørck Nielsen, Hanne.

    In: A C S Applied Materials and Interfaces, Vol. 10, No. 13, 23.02.2018, p. 10678–10687.

    Research output: Contribution to journalJournal articleResearchpeer-review

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