David E. Gloriam

David E. Gloriam

Professor


  1. 2017
  2. Published

    The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site. / Shehata, Mohamed A.; Jensen, Anne Cathrine Nøhr; Jespers, Willem; Floryan, Leonard; Isberg, Vignir; Andersen, Kirsten Bayer; Åqvist, Johan; Gutiérrez-de-Terán, Hugo; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 7, 1128, 25.04.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2016
  4. Published

    GPCRdb : an information system for G protein-coupled receptors. / Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    GPCRdb: The G protein-coupled receptor database - an introduction. / Munk, C; Isberg, V; Mordalski, S; Harpsøe, K; Rataj, K; Hauser, A S; Kolb, P; Bojarski, A J; Vriend, G; Gloriam, D E.

    In: British Journal of Pharmacology, Vol. 173, No. 14, 07.2016, p. 2195-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Integrating structural and mutagenesis data to elucidate GPCR ligand binding. / Munk, Christian; Harpsøe, Kasper; Hauser, Alexander S; Isberg, Vignir; Gloriam, David E.

    In: Current Opinion in Pharmacology, Vol. 30, 10.2016, p. 51-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139. / Shehata, Mohamed A; Jensen, Anne Cathrine Nøhr; Lissa, Delphine; Bisig, Christoph; Isberg, Vignir; Andersen, Kirsten B; Harpsøe, Kasper; Björkling, Fredrik; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 6, 36681, 10.11.2016, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Editorial overview : New technologies: GPCR drug design and function-exploiting the current (of) structures. / Tautermann, Christofer S; Gloriam, David E.

    In: Current Opinion in Pharmacology, Vol. 30, 02.08.2016, p. 7-10.

    Research output: Contribution to journalComment/debateResearch

  9. Published

    Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors. / Xiong, Xiaofeng; Zhang, Hang; Underwood, Christina R.; Harpsøe, Kasper; Gardella, Thomas J.; Wöldike, Mie F.; Mannstadt, Michael; Gloriam, David E.; Bräuner-osborne, Hans; Strømgaard, Kristian.

    In: Nature Chemistry, Vol. 8, No. 11, 2016, p. 1035-1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2015
  11. Published

    Identification and characterization of small molecular NPR-B receptor antagonists. / Andresen, Henriette; Moltzau, Lise; Fagerheim, Steffen; Gloriam, David; Bach, Trond; Levy, Finn.

    In: BMC Pharmacology and Toxicology, Vol. 16, No. Suppl 1, 01.01.2015, p. A70.

    Research output: Contribution to journalJournal articleCommunication

  12. Published

    Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. / Babbitt, Patricia C.; Bagos, Pantelis G.; Bairoch, Amos; Bateman, Alex; Chatonnet, Arnaud; Chen, Mark Jinan; Craik, David J.; Finn, Robert D.; Gloriam, David; Haft, Daniel H.; Henrissat, Bernard; Holliday, Gemma L.; Isberg, Vignir; Kaas, Quentin; Landsman, David; Lenfant, Nicolas; Manning, Gerard; Nagano, Nozomi; Srinivasan, Narayanaswamy; O’Donovan, Claire; Pruitt, Kim D.; Sowdhamini, Ramanathan; Rawlings, Neil D.; Saier, Milton H.; Sharman, Joanna L.; Spedding, Michael; Tsirigos, Konstantinos D.; Vastermark, Ake; Vriend, Gerrit.

    In: Database, Vol. 2015, 18.05.2015, p. 1-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors. / Fidom, Kimberley; Isberg, Vignir; Hauser, Alexander Sebastian; Mordalski, Stefan; Lehto, Thomas; Bojarski, Andrzej J; Gloriam, David E.

    In: Methods, Vol. 71, 01.2015, p. 104-112.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5953796