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Animal models of inflammatory diseases

External factors contributing to variation in disease expression

In particular, the importance of external factors regulating the gut environment during early life period of gestation and weaning that contribute to long-term influence on the hosts immune system is in focus, and how this may impact disease outcome and cause variation in animal models for human inflammatory diseases.

Expert methods within experimental in vivo model research: Germ-free and gnotobiotic mice, antibiotics, modified diets including pro-and prebiotics, cesarean sections, in vivo immunological characterisation. All used to study the impact of gut microbiota on model expression within lab animal science.

http://videnskab.dk/krop-sundhed/dyreforsog-kejsersnit-kan-fa-immunforsvaret-til-fungere-forkert