Anders Bue Klein

Anders Bue Klein

Assistant professor


  1. 2007
  2. Published

    Measurements of brain-derived neurotrophic factor : methodological aspects and demographical data. / Trajkovska, Viktorija; Klein, Anders Bue; Vinberg, Maj; Hartvig, Per; Aznar, Susana; Knudsen, Gitte M.

    In: Brain Research Bulletin, Vol. 73, No. 1-3, 15.06.2007, p. 143-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2008
  4. Published

    Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. / Christensen, R; Marcussen, Anders Bue; Wörtwein, Gitta; Knudsen, G M; Aznar, S.

    In: Experimental Neurology, Vol. 210, No. 1, 2008, p. 164-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats. / Marcussen, Anders Bue; Flagstad, P.; Kristjansen, P.E.G.; Johansen, Flemming Fryd; Englund, U.

    In: Acta Neurologica Scandinavica, Vol. 117, No. 2, 2008, p. 94-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats. / Klein, Anders Bue; Flagstad, P; Kristjansen, P E G; Johansen, F F; Englund, U.

    In: Acta Neurologica Scandinavica, Vol. 117, No. 2, 02.2008, p. 94-100.

    Research output: Contribution to journalJournal articleResearch

  7. 2009
  8. Published

    Activation of glucocorticoid receptors increases 5-HT2A receptor levels. / Trajkovska, Viktorija; Kirkegaard, Lisbeth; Krey, Gesa; Marcussen, Anders Bue; Thomsen, Morten Skøtt; Chourbaji, Sabine; Brandwein, Christiane; Ridder, Stephanie; Halldin, Christer; Gass, Peter; Knudsen, Gitte M; Aznar, Susana.

    In: Experimental Neurology, Vol. 218, No. 1, 2009, p. 83-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures. / Trajkovska, V; Santini, M A; Marcussen, Anders Bue; Thomsen, Morten Skøtt; Hansen, H H; Mikkelsen, Jens D.; Arneberg, L; Kokaia, M; Knudsen, G M; Aznar, S.

    In: Neurochemistry International, Vol. 55, No. 7, 2009, p. 697-702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. / Licht, Cecilie Löe; Marcussen, Anders Bue; Wegener, Gregers; Overstreet, David H; Kleijn, Susana Aznar; Knudsen, Gitte M.

    In: Journal of Neurochemistry, Vol. 109, No. 5, 01.06.2009, p. 1363-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2010
  12. Published

    Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. / Holm, Peter; Ettrup, Anders; Klein, Anders B; Santini, Martin A; El-Sayed, Mona; Elvang, Anders B; Stensbøl, Tine B; Mikkelsen, Jens D; Knudsen, Gitte M; Kleijn, Susana Aznar.

    In: Journal of Alzheimer's Disease, Vol. 20, No. 4, 01.01.2010, p. 1201-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. / Aznar, Susana; Klein, Anders B; Santini, Martin A; Knudsen, Gitte M; Henn, Fritz; Gass, Peter; Vollmayr, Barbara.

    In: Synapse, Vol. 64, No. 7, 01.07.2010, p. 561-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Changes in 5-HT2A-mediated behavior and 5-HT2A- and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. / Klein, A B; Santini, M A; Aznar, S; Knudsen, G M; Rios, M.

    In: Laser Neuroscience, Vol. 169, No. 3, 01.09.2010, p. 1007-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. / Klein, Anders Bue; Trajkovska, Viktorija; Erritzoe, David; Haugbol, Steven; Madsen, Jacob; Baaré, William; Aznar, Susana; Knudsen, Gitte M.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 30, No. 11, 01.11.2010, p. e1-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2012
  18. Published

    Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration. / Ziebell, Morten; Khalid, Usman; Klein, Anders B; Aznar, Susana; Thomsen, Gerda; Jensen, Peter; Knudsen, Gitte M; Jensen, Peter Steen.

    In: Neurobiology of Aging, Vol. 33, No. 2, 2012, p. 428.e1-428.e5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. The microtubule-associated protein 1A (MAP1A) is an early molecular target of soluble Aβ-peptide. / Clemmensen, C; Aznar, S; Knudsen, G M; Klein, A B; Klein, Anders Bue.

    In: Cellular & Molecular Neurobiology, Vol. 32, No. 4, 05.2012, p. 561-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice. / Reverte, Ingrid; Klein, Anders Bue; Ratner, Cecilia; Domingo, José L; Colomina, Maria Teresa.

    In: Experimental Neurology, Vol. 237, No. 1, 09.2012, p. 116-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2013
  22. Published

    Cognitive performance of Göttingen minipigs is affected by diet in a spatial hole-board discrimination test. / Haagensen, Annika Maria Juul; Klein, Anders Bue; Ettrup, Anders; Matthews, Lindsay R.; Sørensen, Dorte Bratbo.

    In: PloS one, Vol. 8, No. 11, e79429, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Enhanced voluntary wheel running in GPRC6A receptor knockout mice. / Clemmensen, Christoffer; Pehmøller, Christian; Klein, Anders B; Ratner, Cecilia; Wojtaszewski, Jørgen; Bräuner-Osborne, Hans.

    In: Physiology & Behavior, Vol. 118, 2013, p. 144-151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice. / Clemmensen, Christoffer; Smajilovic, Sanela; Madsen, Andreas N; Klein, Anders B; Holst, Birgitte; Bräuner-Osborne, Hans.

    In: Journal of Endocrinology, Vol. 217, No. 2, 2013, p. 151-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons. / Jørgensen, Christinna Vangsgaard; Klein, Anders Bue; El-Sayed, Mona; Knudsen, Gitte M; Mikkelsen, Jens D.

    In: Synapse, Vol. 67, No. 11, 2013, p. 794-800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Transient activation of mTOR following forced treadmill exercise in rats. / Elfving, Betina; Christensen, Tina; Ratner, Cecilia; Wienecke, Jacob; Klein, Anders B.

    In: Synapse, Vol. 67, No. 9, 2013, p. 620-625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia. / Santini, Martin A; Ratner, Cecilia Friis; Aznar, Susana; Klein, Anders B; Knudsen, Gitte M; Mikkelsen, Jens D; Klein, Anders Bue.

    In: Journal of Neuroscience Research, Vol. 91, No. 5, 05.2013, p. 634-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Regulating prefrontal cortex activation : an emerging role for the 5-HT2A serotonin receptor in the modulation of emotion-based actions? / Aznar, Susana; Klein, Anders Bue.

    In: Molecular Neurobiology, Vol. 48, No. 3, 22.05.2013, p. 841-853.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy. / Klein, Anders B; Jennum, Poul; Knudsen, Stine; Gammeltoft, Steen; Mikkelsen, Jens D.

    In: Neuroscience Letters, Vol. 544, 07.06.2013, p. 31-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. / Jørgensen, Christinna Vangsgaard; Jacobsen, Jacob P; Caron, Marc G; Klein, Anders Bue; Knudsen, Gitte M; Mikkelsen, Jens D.

    In: Neuroscience Letters, Vol. 555, 25.10.2013, p. 118-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2014
  32. Published

    A possible link between food and mood : dietary impact on gut microbiota and behavior in BALB/c mice. / Jørgensen, Bettina Merete Pyndt; Hansen, Julie Torpe; Krych, Lukasz; Larsen, Christian Schiøth; Klein, Anders Bue; Nielsen, Dennis Sandris; Josefsen, Knud; Hansen, Axel Kornerup; Sørensen, Dorte Bratbo.

    In: PLOS ONE, Vol. 9, No. 8, 2014, p. e103398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    GHB receptor targets in the CNS: Focus on high-affinity binding sites. / Bay, Tina; Eghorn, Laura Friis; Klein, Anders Bue; Wellendorph, Petrine.

    In: Biochemical Pharmacology, Vol. 87, No. 2, 2014, p. 220-228.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Long term effects of murine postnatal exposure to decabromodiphenyl ether (BDE-209) on learning and memory are dependent upon APOE polymorphism and age. / Reverte, Ingrid; Klein, Anders Bue; Domingo, José L; Colomina, Maria Teresa.

    In: Neurotoxicology and Teratology, Vol. 40, 2014, p. 17-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains. / Klein, A B; Ultved, L; Adamsen, D; Santini, Martin A; Tobeña, A; Fernandez-Teruel, A; Flores, P; Moreno, M; Cardona, D; Knudsen, Gitte Moos; Aznar, Susana; Mikkelsen, J D.

    In: Neuroscience, Vol. 263, 28.03.2014, p. 36-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated. / Thomsen, Morten Skøtt; Cinar, Betül; Jensen, Majbrit Myrup; Lyukmanova, Ekaterina N; Shulepko, Mikhail A; Tsetlin, Victor; Klein, Anders Bue; Mikkelsen, Jens D.

    In: Brain Structure and Function (Print Edition), Vol. 219, No. 6, 17.11.2014, p. 1923-1934.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2015
  38. Published

    BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. / Fisher, Patrick M; Holst, Klaus K; Adamsen, Dea; Klein, Anders Bue; Frokjaer, Vibe G; Jensen, Peter S; Svarer, Claus; Gillings, Nic; Baare, William F C; Mikkelsen, Jens D; Knudsen, Gitte M.

    In: Human Brain Mapping, Vol. 36, No. 1, 01.2015, p. 313–323.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression. / Visser, Anniek Kd; Ettrup, Anders; Klein, Anders Bue; van Waarde, Aren; Bosker, Fokko J; Meerlo, Peter; Knudsen, Gitte M; de Boer, Sietse F.

    In: Synapse (New York, N.Y.), Vol. 69, No. 4, 13.02.2015, p. 226–232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Demonstration of the dynamic mass redistribution label-free technology as a useful cell-based pharmacological assay for endogenously expressed GABAA receptors. / Klein, Anders Bue; Nittegaard-Nielsen, Mia; Christensen, Julie T.; Al-Khawaja, Anas; Wellendorph, Petrine.

    In: MedChemComm, Vol. 7, 19.11.2015, p. 426-432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2016
  42. Published

    5-HT2A Receptor Binding in the Frontal Cortex of Parkinson's Disease Patients and Alpha-Synuclein Overexpressing Mice : A Postmortem Study. / Rasmussen, Nadja Bredo; Olesen, Mikkel Vestergaard; Brudek, Tomasz; Plenge, Per; Klein, Anders Bue; Westin, Jenny E.; Fog, Karina; Wörtwein, Gitta; Aznar, Susana.

    In: Parkinson’s Disease, Vol. 2016, 3682936, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Radiosynthesis and characterisation of a potent and selective GPR139 agonist radioligand. / Kuhne, Sebastiaan; Nøhr, Anne Cathrine; Marek, AleŠ; Elbert, TomáŠ; Klein, Anders Bue; Bräuner-Osborne, Hans; Wellendorph, Petrine; Pedersen, Daniel Sejer.

    In: RSC Advances, Vol. 6, No. 2, 2016, p. 947-952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Functional interaction between Lypd6 and nicotinic acetylcholine receptors. / Arvaniti, Maria; Jensen, Majbrit M; Soni, Neeraj; Wang, Hong; Klein, Anders B; Thiriet, Nathalie; Pinborg, Lars H; Muldoon, Pretal P; Wienecke, Jacob; Imad Damaj, M; Kohlmeier, Kristi A; Gondré-Lewis, Marjorie C; Mikkelsen, Jens D; Thomsen, Morten S.

    In: Journal of Neurochemistry, Vol. 138, No. 6, 09.2016, p. 806-820.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using (3)H-HOCPCA. / Klein, A B; Bay, T; Villumsen, I S; Falk-Petersen, C B; Marek, A; Frølund, B; Clausen, R P; Hansen, Hanne Demant; Knudsen, G M; Wellendorph, P.

    In: Neurochemistry International, Vol. 100, 11.2016, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2017
  47. Published

    Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings. / Bader, Benjamin M; Steder, Anne; Klein, Anders Bue; Frølund, Bente; Schroeder, Olaf H U; Jensen, Anders A.

    In: PloS One, Vol. 12, No. 10, e0186147, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    International consensus statement on the peri-operative management of anaemia and iron deficiency. / Muñoz, M.; Acheson, A. G.; Auerbach, M.; Besser, M.; Habler, O.; Kehlet, H.; Liumbruno, G. M.; Lasocki, S.; Meybohm, P.; Rao Baikady, R.; Richards, T.; Shander, A.; So-Osman, C.; Spahn, D. R.; Klein, A. A.

    In: Anaesthesia, Vol. 72, No. 2, 02.2017, p. 233-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Tryptophan depletion affects compulsive behaviour in rats : strain dependent effects and associated neuromechanisms. / Merchán, A; Navarro, S V; Klein, A B; Aznar, S; Campa, L; Suñol, C; Moreno, M; Flores, P.

    In: Psychopharmacology, Vol. 234, No. 8, 04.2017, p. 1223-1236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes. / Falk-Petersen, Christina B; Søgaard, Rikke; Madsen, Kenneth L; Klein, Anders B; Frølund, Bente; Wellendorph, Petrine.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 121, No. 2, 08.2017, p. 119-129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2018
  52. Published

    Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus. / Söderhielm, Pella Cecilia; Klein, Anders Bue; Bomholtz, Sofia Hammami; Jensen, Anders A.

    In: Life Sciences, Vol. 214, 2018, p. 145-152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Reduced cortical serotonin 5-HT2A receptor binding and glutamate activity in high compulsive drinker rats. / Mora, Santiago; Merchán, Ana; Vilchez, Olga; Aznar, Susana; Klein, Anders Bue; Ultved, Lene; Campa, Leticia; Suñol, Cristina; Flores, Pilar; Moreno, Margarita.

    In: Neuropharmacology, Vol. 143, 2018, p. 10-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Differences in 5-HT2A and mGlu2 Receptor Expression Levels and Repressive Epigenetic Modifications at the 5-HT2A Promoter Region in the Roman Low- (RLA-I) and High- (RHA-I) Avoidance Rat Strains. / Fomsgaard, Luna; Moreno, Jose L; de la Fuente Revenga, Mario; Brudek, Tomasz; Adamsen, Dea; Rio-Alamos, Cristobal; Saunders, Justin; Klein, Anders Bue; Oliveras, Ignasi; Cañete, Toni; Blazquez, Gloria; Tobeña, Adolf; Fernandez-Teruel, Albert; Gonzalez-Maeso, Javier; Aznar, Susana.

    In: Molecular Neurobiology, Vol. 55, No. 3, 03.2018, p. 1998–2012 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2019
  56. Published

    Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets. / Griem-Krey, Nane; Klein, Anders Bue; Herth, Matthias; Wellendorph, Petrine.

    In: Journal of visualized experiments : JoVE, No. 145, e58879, 12.03.2019.

    Research output: Contribution to journalJournal articleCommunication

  57. Accepted/In press

ID: 33971093