Syndecans: synergistic activators of cell adhesion.
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Syndecans: synergistic activators of cell adhesion. / Woods, A; Couchman, J R.
In: Trends in Cell Biolology, Vol. 8, No. 5, 1998, p. 189-92.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Syndecans: synergistic activators of cell adhesion.
AU - Woods, A
AU - Couchman, J R
N1 - Keywords: Amino Acid Sequence; Animals; Cell Adhesion; Cell Communication; Drug Synergism; Humans; Membrane Glycoproteins; Molecular Sequence Data; Proteoglycans; Signal Transduction; Syndecans
PY - 1998
Y1 - 1998
N2 - Cell-surface proteoglycans participate in cell adhesion, growth-factor signalling, lipase activity and anticoagulation. Until recently, only the roles of the glycosaminoglycan chains were investigated. Now, with molecular characterization of several core proteins, the roles of each individual proteoglycan species in cellular signalling pathways are being determined. This review describes some of the recent advances in our understanding of the major transmembrane group of heparan sulfate proteoglycans, the syndecans, including evidence that they play an important role as accessory signalling molecules modulating integrin-based adhesion.
AB - Cell-surface proteoglycans participate in cell adhesion, growth-factor signalling, lipase activity and anticoagulation. Until recently, only the roles of the glycosaminoglycan chains were investigated. Now, with molecular characterization of several core proteins, the roles of each individual proteoglycan species in cellular signalling pathways are being determined. This review describes some of the recent advances in our understanding of the major transmembrane group of heparan sulfate proteoglycans, the syndecans, including evidence that they play an important role as accessory signalling molecules modulating integrin-based adhesion.
M3 - Journal article
C2 - 9695837
VL - 8
SP - 189
EP - 192
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 5
ER -
ID: 5164513