Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium

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Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. / Barrow, Hannah; Guo, Xiuli; Wandall, Hans H; Pedersen, Johannes W; Fu, Bo; Zhao, Qicheng; Chen, Chen; Rhodes, Jonathan M; Yu, Lu-Gang.

In: Clinical Cancer Research, Vol. 17, No. 22, 15.11.2011, p. 7035-7046.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Barrow, H, Guo, X, Wandall, HH, Pedersen, JW, Fu, B, Zhao, Q, Chen, C, Rhodes, JM & Yu, L-G 2011, 'Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium', Clinical Cancer Research, vol. 17, no. 22, pp. 7035-7046. https://doi.org/10.1158/1078-0432.CCR-11-1462

APA

Barrow, H., Guo, X., Wandall, H. H., Pedersen, J. W., Fu, B., Zhao, Q., Chen, C., Rhodes, J. M., & Yu, L-G. (2011). Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. Clinical Cancer Research, 17(22), 7035-7046. https://doi.org/10.1158/1078-0432.CCR-11-1462

Vancouver

Barrow H, Guo X, Wandall HH, Pedersen JW, Fu B, Zhao Q et al. Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. Clinical Cancer Research. 2011 Nov 15;17(22):7035-7046. https://doi.org/10.1158/1078-0432.CCR-11-1462

Author

Barrow, Hannah ; Guo, Xiuli ; Wandall, Hans H ; Pedersen, Johannes W ; Fu, Bo ; Zhao, Qicheng ; Chen, Chen ; Rhodes, Jonathan M ; Yu, Lu-Gang. / Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. In: Clinical Cancer Research. 2011 ; Vol. 17, No. 22. pp. 7035-7046.

Bibtex

@article{9b8570258bf14721b1ee26fd629906db,
title = "Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium",
abstract = "Adhesion of disseminating tumor cells to the blood vascular endothelium is a pivotal step in metastasis. Previous investigations have shown that galectin-3 concentrations are increased in the bloodstream of patients with cancer and that galectin-3 promotes adhesion of disseminating tumor cells to vascular endothelium in vitro and experimental metastasis in vivo. This study determined the levels of galectin-1, -2, -3, -4, -8, and -9 in the sera of healthy people and patients with colon and breast cancer and assessed the influence of these galectins on cancer-endothelium adhesion.",
author = "Hannah Barrow and Xiuli Guo and Wandall, {Hans H} and Pedersen, {Johannes W} and Bo Fu and Qicheng Zhao and Chen Chen and Rhodes, {Jonathan M} and Lu-Gang Yu",
year = "2011",
month = nov,
day = "15",
doi = "10.1158/1078-0432.CCR-11-1462",
language = "English",
volume = "17",
pages = "7035--7046",
journal = "Clinical Cancer Research",
issn = "1078-0432",
publisher = "American Association for Cancer Research (A A C R)",
number = "22",

}

RIS

TY - JOUR

T1 - Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium

AU - Barrow, Hannah

AU - Guo, Xiuli

AU - Wandall, Hans H

AU - Pedersen, Johannes W

AU - Fu, Bo

AU - Zhao, Qicheng

AU - Chen, Chen

AU - Rhodes, Jonathan M

AU - Yu, Lu-Gang

PY - 2011/11/15

Y1 - 2011/11/15

N2 - Adhesion of disseminating tumor cells to the blood vascular endothelium is a pivotal step in metastasis. Previous investigations have shown that galectin-3 concentrations are increased in the bloodstream of patients with cancer and that galectin-3 promotes adhesion of disseminating tumor cells to vascular endothelium in vitro and experimental metastasis in vivo. This study determined the levels of galectin-1, -2, -3, -4, -8, and -9 in the sera of healthy people and patients with colon and breast cancer and assessed the influence of these galectins on cancer-endothelium adhesion.

AB - Adhesion of disseminating tumor cells to the blood vascular endothelium is a pivotal step in metastasis. Previous investigations have shown that galectin-3 concentrations are increased in the bloodstream of patients with cancer and that galectin-3 promotes adhesion of disseminating tumor cells to vascular endothelium in vitro and experimental metastasis in vivo. This study determined the levels of galectin-1, -2, -3, -4, -8, and -9 in the sera of healthy people and patients with colon and breast cancer and assessed the influence of these galectins on cancer-endothelium adhesion.

U2 - 10.1158/1078-0432.CCR-11-1462

DO - 10.1158/1078-0432.CCR-11-1462

M3 - Journal article

C2 - 21933892

VL - 17

SP - 7035

EP - 7046

JO - Clinical Cancer Research

JF - Clinical Cancer Research

SN - 1078-0432

IS - 22

ER -

ID: 37622261