Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Intestinal permeability and glucagon-like peptide-2 in children with autism : a controlled pilot study. / Robertson, Marli A; Sigalet, David L; Holst, Jens Juul; Meddings, Jon B; Wood, Julie; Sharkey, Keith A.

In: Journal of Autism and Developmental Disorders, Vol. 38, No. 6, 07.2008, p. 1066-71.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Robertson, MA, Sigalet, DL, Holst, JJ, Meddings, JB, Wood, J & Sharkey, KA 2008, 'Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study', Journal of Autism and Developmental Disorders, vol. 38, no. 6, pp. 1066-71. https://doi.org/10.1007/s10803-007-0482-1

APA

Robertson, M. A., Sigalet, D. L., Holst, J. J., Meddings, J. B., Wood, J., & Sharkey, K. A. (2008). Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study. Journal of Autism and Developmental Disorders, 38(6), 1066-71. https://doi.org/10.1007/s10803-007-0482-1

Vancouver

Robertson MA, Sigalet DL, Holst JJ, Meddings JB, Wood J, Sharkey KA. Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study. Journal of Autism and Developmental Disorders. 2008 Jul;38(6):1066-71. https://doi.org/10.1007/s10803-007-0482-1

Author

Robertson, Marli A ; Sigalet, David L ; Holst, Jens Juul ; Meddings, Jon B ; Wood, Julie ; Sharkey, Keith A. / Intestinal permeability and glucagon-like peptide-2 in children with autism : a controlled pilot study. In: Journal of Autism and Developmental Disorders. 2008 ; Vol. 38, No. 6. pp. 1066-71.

Bibtex

@article{6095c47d7c2a43438dce53549e8e2c2c,
title = "Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study",
abstract = "We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.",
keywords = "Autistic Disorder, Child, Child, Preschool, Female, Glucagon-Like Peptide 2, Humans, Intestinal Absorption, Intestine, Small, Lactulose, Male, Mannitol, Pilot Projects, Reference Values, Satiety Response",
author = "Robertson, {Marli A} and Sigalet, {David L} and Holst, {Jens Juul} and Meddings, {Jon B} and Julie Wood and Sharkey, {Keith A}",
year = "2008",
month = jul,
doi = "10.1007/s10803-007-0482-1",
language = "English",
volume = "38",
pages = "1066--71",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Intestinal permeability and glucagon-like peptide-2 in children with autism

T2 - a controlled pilot study

AU - Robertson, Marli A

AU - Sigalet, David L

AU - Holst, Jens Juul

AU - Meddings, Jon B

AU - Wood, Julie

AU - Sharkey, Keith A

PY - 2008/7

Y1 - 2008/7

N2 - We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.

AB - We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.

KW - Autistic Disorder

KW - Child

KW - Child, Preschool

KW - Female

KW - Glucagon-Like Peptide 2

KW - Humans

KW - Intestinal Absorption

KW - Intestine, Small

KW - Lactulose

KW - Male

KW - Mannitol

KW - Pilot Projects

KW - Reference Values

KW - Satiety Response

U2 - 10.1007/s10803-007-0482-1

DO - 10.1007/s10803-007-0482-1

M3 - Journal article

C2 - 18311517

VL - 38

SP - 1066

EP - 1071

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 6

ER -

ID: 132049280