Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index : the DIOGENES trial 12-months results. / Aller, E E J G; Larsen, Thomas Meinert; Holst, Claus; Karin Lindroos, A; Kafatos, A; Pfeiffer, A; Martinez, J A; Handjieva-Darlenska, T; Kunesova, M; Stender, Steen; Saris, W H M; Astrup, Arne; van Baak, M A.

In: International Journal of Obesity, Vol. 38, No. 12, 2014, p. 1511-1517.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Aller, EEJG, Larsen, TM, Holst, C, Karin Lindroos, A, Kafatos, A, Pfeiffer, A, Martinez, JA, Handjieva-Darlenska, T, Kunesova, M, Stender, S, Saris, WHM, Astrup, A & van Baak, MA 2014, 'Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results', International Journal of Obesity, vol. 38, no. 12, pp. 1511-1517. https://doi.org/10.1038/ijo.2014.52

APA

Aller, E. E. J. G., Larsen, T. M., Holst, C., Karin Lindroos, A., Kafatos, A., Pfeiffer, A., Martinez, J. A., Handjieva-Darlenska, T., Kunesova, M., Stender, S., Saris, W. H. M., Astrup, A., & van Baak, M. A. (2014). Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results. International Journal of Obesity, 38(12), 1511-1517. https://doi.org/10.1038/ijo.2014.52

Vancouver

Aller EEJG, Larsen TM, Holst C, Karin Lindroos A, Kafatos A, Pfeiffer A et al. Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results. International Journal of Obesity. 2014;38(12):1511-1517. https://doi.org/10.1038/ijo.2014.52

Author

Aller, E E J G ; Larsen, Thomas Meinert ; Holst, Claus ; Karin Lindroos, A ; Kafatos, A ; Pfeiffer, A ; Martinez, J A ; Handjieva-Darlenska, T ; Kunesova, M ; Stender, Steen ; Saris, W H M ; Astrup, Arne ; van Baak, M A. / Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index : the DIOGENES trial 12-months results. In: International Journal of Obesity. 2014 ; Vol. 38, No. 12. pp. 1511-1517.

Bibtex

@article{a5fedf3355664b6a979a4150c3a82d07,
title = "Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results",
abstract = "Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95% CI)). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P",
author = "Aller, {E E J G} and Larsen, {Thomas Meinert} and Claus Holst and {Karin Lindroos}, A and A Kafatos and A Pfeiffer and Martinez, {J A} and T Handjieva-Darlenska and M Kunesova and Steen Stender and Saris, {W H M} and Arne Astrup and {van Baak}, {M A}",
note = "CURIS 2014 NEXS 097",
year = "2014",
doi = "10.1038/ijo.2014.52",
language = "English",
volume = "38",
pages = "1511--1517",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "12",

}

RIS

TY - JOUR

T1 - Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index

T2 - the DIOGENES trial 12-months results

AU - Aller, E E J G

AU - Larsen, Thomas Meinert

AU - Holst, Claus

AU - Karin Lindroos, A

AU - Kafatos, A

AU - Pfeiffer, A

AU - Martinez, J A

AU - Handjieva-Darlenska, T

AU - Kunesova, M

AU - Stender, Steen

AU - Saris, W H M

AU - Astrup, Arne

AU - van Baak, M A

N1 - CURIS 2014 NEXS 097

PY - 2014

Y1 - 2014

N2 - Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95% CI)). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P

AB - Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95% CI)). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P

U2 - 10.1038/ijo.2014.52

DO - 10.1038/ijo.2014.52

M3 - Journal article

C2 - 24675714

VL - 38

SP - 1511

EP - 1517

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 12

ER -

ID: 105853128