Ny markør ved trombotisk trombocytopenisk purpura.
Research output: Contribution to journal › Journal article › Research › peer-review
Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP.
|Translated title of the contribution||New marker in thrombotic thrombocytopenic purpura|
|Journal||Ugeskrift for læger|
|Number of pages||3|
|Publication status||Published - 2008|
Keywords: ADAM Proteins; Biological Markers; Diagnosis, Differential; Humans; Purpura, Thrombotic Thrombocytopenic; von Willebrand Factor