Nickel allergy in a Danish population 25 years after the first nickel regulation
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Nickel allergy in a Danish population 25 years after the first nickel regulation. / Ahlström, Malin G.; Menné, Torkil; Thyssen, Jacob P.; Johansen, Jeanne D.
In: Contact Dermatitis, Vol. 76, No. 6, 2017, p. 325-332.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Nickel allergy in a Danish population 25 years after the first nickel regulation
AU - Ahlström, Malin G.
AU - Menné, Torkil
AU - Thyssen, Jacob P.
AU - Johansen, Jeanne D.
PY - 2017
Y1 - 2017
N2 - Background: Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation. Objectives: To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. Methods: A questionnaire was sent to all patients who reacted positively to nickel sulfate 5% pet. within the last 5 years at the Department of Dermatology and Allergy, Gentofte Hospital. Results: The response rate was 63.2%. Earrings were the foremost cause of dermatitis after the EU Nickel Directive had been implemented, followed by other jewellery, buttons on clothing, belt buckles, and wrist watches. Dermatitis reactions within 10 min of contact were reported by 21.4% of patients, and dermatitis reactions within 30 min of contact were reported by 30.7% of patients. Conclusions: Nickel exposures that led to the implementation of a nickel regulation seem to persist. The durations of contact with metallic items to fall under the current REACH regulation of nickel correspond well with the results of this study.
AB - Background: Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation. Objectives: To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. Methods: A questionnaire was sent to all patients who reacted positively to nickel sulfate 5% pet. within the last 5 years at the Department of Dermatology and Allergy, Gentofte Hospital. Results: The response rate was 63.2%. Earrings were the foremost cause of dermatitis after the EU Nickel Directive had been implemented, followed by other jewellery, buttons on clothing, belt buckles, and wrist watches. Dermatitis reactions within 10 min of contact were reported by 21.4% of patients, and dermatitis reactions within 30 min of contact were reported by 30.7% of patients. Conclusions: Nickel exposures that led to the implementation of a nickel regulation seem to persist. The durations of contact with metallic items to fall under the current REACH regulation of nickel correspond well with the results of this study.
KW - allergic nickel dermatitis
KW - EU directive
KW - metallic items
KW - nickel
KW - prolonged direct contact
U2 - 10.1111/cod.12782
DO - 10.1111/cod.12782
M3 - Journal article
C2 - 28386993
AN - SCOPUS:85017442369
VL - 76
SP - 325
EP - 332
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 6
ER -
ID: 196440643