Mitochondrial Plasticity With Exercise Training and Extreme Environments
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Mitochondrial Plasticity With Exercise Training and Extreme Environments. / Boushel, Robert; Lundby, Carsten; Qvortrup, Klaus; Sahlin, Kent.
In: Exercise and Sport Sciences Reviews, Vol. 42, No. 4, 10.2014, p. 169-74.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Mitochondrial Plasticity With Exercise Training and Extreme Environments
AU - Boushel, Robert
AU - Lundby, Carsten
AU - Qvortrup, Klaus
AU - Sahlin, Kent
PY - 2014/10
Y1 - 2014/10
N2 - Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity and biochemical coupling efficiency may be differentially regulated with training and exposure to extreme environments. Threshold training doses inducing mitochondrial up-regulation remain to be elucidated considering fitness level.SUMMARY: Muscle mitochondrial are responsive to training and environment, yet thresholds for volume vs. regulatory changes and their physiological significance remain to be explored.
AB - Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity and biochemical coupling efficiency may be differentially regulated with training and exposure to extreme environments. Threshold training doses inducing mitochondrial up-regulation remain to be elucidated considering fitness level.SUMMARY: Muscle mitochondrial are responsive to training and environment, yet thresholds for volume vs. regulatory changes and their physiological significance remain to be explored.
U2 - 10.1249/JES.0000000000000025
DO - 10.1249/JES.0000000000000025
M3 - Journal article
C2 - 25062000
VL - 42
SP - 169
EP - 174
JO - Exercise and Sport Sciences Reviews
JF - Exercise and Sport Sciences Reviews
SN - 0091-6331
IS - 4
ER -
ID: 119464219