Is there a risk of active sensitization to PPD by patch testing the general population?

Research output: Contribution to journalJournal articleResearchpeer-review

Para-phenylenediamine (PPD), a constituent of permanent hair dyes, may cause contact allergy in exposed individuals. It has previously been questioned whether a patch testing with PPD in population-based epidemiological studies is entirely safe. The Glostrup allergy studies patch tested the same cohort twice. In 1990, 567 persons were patch-tested and only one person had a (+) positive reaction to PPD. In 1998, 540 persons were re-invited to a new patch test and 365 (participation rate 68%) were re-tested. There were no positive reactions to PPD. These studies indicate that patch testing with PPD in individuals with no previous positive reactions to PPD or with only one previous positive reaction does not cause active sensitization and can be performed with minimal risk.

Original languageEnglish
JournalContact Dermatitis
Issue number2
Pages (from-to)133-4
Number of pages2
Publication statusPublished - Aug 2007
Externally publishedYes

    Research areas

  • Allergens, Coloring Agents, Denmark, Dermatitis, Allergic Contact, Humans, Patch Tests, Phenylenediamines, Risk Factors, Journal Article, Research Support, Non-U.S. Gov't

ID: 173162250