Impact of hand eczema on quality of life: metropolitan versus non-metropolitan areas
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Impact of hand eczema on quality of life : metropolitan versus non-metropolitan areas. / Nørreslet, Line B.; Agner, Tove; Sørensen, Jennifer A.; Ebbehøj, Niels E.; Bonde, Jens P.; Fisker, Maja H.
In: Contact Dermatitis, Vol. 78, No. 5, 2018, p. 348-354.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Impact of hand eczema on quality of life
T2 - metropolitan versus non-metropolitan areas
AU - Nørreslet, Line B.
AU - Agner, Tove
AU - Sørensen, Jennifer A.
AU - Ebbehøj, Niels E.
AU - Bonde, Jens P.
AU - Fisker, Maja H.
PY - 2018
Y1 - 2018
N2 - Background: An inverse relationship between disease severity and health-related quality of life (HR-QoL) in patients with hand eczema is well established, but modifying effects of demographic variables have been less well studied. Objective: To identify the influence of metropolitan versus non-metropolitan residence on the relationship between disease severity and HR-QoL in patients with occupational hand eczema. Methods: The city of Copenhagen and the rest of Zealand were defined as metropolitan and non-metropolitan areas, respectively. Participants were 773 persons with occupational hand eczema. A questionnaire on the severity of hand eczema and HR-QoL was sent to all participants. Results: The odds for reporting moderate to high severity of occupational hand eczema were significantly lower in the metropolitan population than in the non-metropolitan population [odds ratio (OR): 0.42; 95%CI: 0.23–0.75], whereas low dermatology-related quality of life was more prevalent in metropolitan than in non-metropolitan patients (OR: 1.31; 95%CI: 0.83–2.05), indicating that hand eczema had a more pronounced negative effect in metropolitan patients, in spite of less severe eczema. Conclusion: Our data indicate that area of residence has a modifying effect on the relationship between disease severity and HR-QoL, with a more negative impact on HR-QoL in metropolitan than in non-metropolitan areas. This information is important with respect to fully appreciating the burden of occupational hand eczema.
AB - Background: An inverse relationship between disease severity and health-related quality of life (HR-QoL) in patients with hand eczema is well established, but modifying effects of demographic variables have been less well studied. Objective: To identify the influence of metropolitan versus non-metropolitan residence on the relationship between disease severity and HR-QoL in patients with occupational hand eczema. Methods: The city of Copenhagen and the rest of Zealand were defined as metropolitan and non-metropolitan areas, respectively. Participants were 773 persons with occupational hand eczema. A questionnaire on the severity of hand eczema and HR-QoL was sent to all participants. Results: The odds for reporting moderate to high severity of occupational hand eczema were significantly lower in the metropolitan population than in the non-metropolitan population [odds ratio (OR): 0.42; 95%CI: 0.23–0.75], whereas low dermatology-related quality of life was more prevalent in metropolitan than in non-metropolitan patients (OR: 1.31; 95%CI: 0.83–2.05), indicating that hand eczema had a more pronounced negative effect in metropolitan patients, in spite of less severe eczema. Conclusion: Our data indicate that area of residence has a modifying effect on the relationship between disease severity and HR-QoL, with a more negative impact on HR-QoL in metropolitan than in non-metropolitan areas. This information is important with respect to fully appreciating the burden of occupational hand eczema.
KW - health-related quality of life
KW - metropolitan residence
KW - occupational hand eczema
U2 - 10.1111/cod.12962
DO - 10.1111/cod.12962
M3 - Journal article
C2 - 29457230
AN - SCOPUS:85042166326
VL - 78
SP - 348
EP - 354
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 5
ER -
ID: 217393560