Contraction-associated translocation of protein kinase C in rat skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Contraction-associated translocation of protein kinase C in rat skeletal muscle. / Richter, Erik A.; Cleland, P J; Rattigan, S; Clark, M G.
In: FEBS Letters, Vol. 217, No. 2, 1987, p. 232-236.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Contraction-associated translocation of protein kinase C in rat skeletal muscle
AU - Richter, Erik A.
AU - Cleland, P J
AU - Rattigan, S
AU - Clark, M G
PY - 1987
Y1 - 1987
N2 - Electrical stimulation of the sciatic nerve of the anaesthetized rat in vivo led to a time-dependent translocation of protein kinase C from the muscle cytosol to the particulate fraction. Maximum activity of protein kinase C in the particulate fraction occurred after 2 min of intermittent short tetanic contractions of the gastrocnemius-plantaris-soleus muscle group and coincided with the loss of activity from the cytosol. Translocation of protein kinase C may imply a role for this kinase in contraction-initiated changes in muscle metabolism.
AB - Electrical stimulation of the sciatic nerve of the anaesthetized rat in vivo led to a time-dependent translocation of protein kinase C from the muscle cytosol to the particulate fraction. Maximum activity of protein kinase C in the particulate fraction occurred after 2 min of intermittent short tetanic contractions of the gastrocnemius-plantaris-soleus muscle group and coincided with the loss of activity from the cytosol. Translocation of protein kinase C may imply a role for this kinase in contraction-initiated changes in muscle metabolism.
KW - Animals
KW - Biological Transport
KW - Calcium
KW - Cytosol
KW - Kinetics
KW - Male
KW - Muscle Contraction
KW - Muscles
KW - Phospholipids
KW - Protein Kinase C
KW - Rats
KW - Rats, Inbred Strains
KW - Subcellular Fractions
M3 - Journal article
C2 - 3595854
VL - 217
SP - 232
EP - 236
JO - F E B S Letters
JF - F E B S Letters
SN - 0014-5793
IS - 2
ER -
ID: 154757954