Azotides as Modular Peptide-Based Ligands for Asymmetric Lewis Acid Catalysis
Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of azotides and evaluation of these as ligands for enantioselective Lewis acid catalysis is reported. The ligands were readily prepared from the chiral pool of amino acids and perform well in the cobalt(II)-catalyzed formation of asymmetric hetero Diels-Alder adducts. A rational for the observed enantioselectivity and conversion rate supported by computational calculations is provided.
|Journal||Journal of Organic Chemistry|
|Number of pages||6|
|Publication status||Published - 7 Jun 2019|