Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men

Research output: Contribution to journalJournal articlepeer-review

Standard

Young adult predictors of alcohol dependence to age 53 : a 44-year prospective cohort study of Danish men. / Sørensen, Holger J; Manzardo, Ann; Just-Østergaard, Emilie; Penick, Elizabeth C; Becker, Ulrik M D; Mortensen, Erik Lykke; Knop, Joachim.

In: Addiction, Vol. 116, No. 4, 2021, p. 780-787.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Sørensen, HJ, Manzardo, A, Just-Østergaard, E, Penick, EC, Becker, UMD, Mortensen, EL & Knop, J 2021, 'Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men', Addiction, vol. 116, no. 4, pp. 780-787. https://doi.org/10.1111/add.15209

APA

Sørensen, H. J., Manzardo, A., Just-Østergaard, E., Penick, E. C., Becker, U. M. D., Mortensen, E. L., & Knop, J. (2021). Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men. Addiction, 116(4), 780-787. https://doi.org/10.1111/add.15209

Vancouver

Sørensen HJ, Manzardo A, Just-Østergaard E, Penick EC, Becker UMD, Mortensen EL et al. Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men. Addiction. 2021;116(4):780-787. https://doi.org/10.1111/add.15209

Author

Sørensen, Holger J ; Manzardo, Ann ; Just-Østergaard, Emilie ; Penick, Elizabeth C ; Becker, Ulrik M D ; Mortensen, Erik Lykke ; Knop, Joachim. / Young adult predictors of alcohol dependence to age 53 : a 44-year prospective cohort study of Danish men. In: Addiction. 2021 ; Vol. 116, No. 4. pp. 780-787.

Bibtex

@article{fa52491e0c3c4ea482f8f566134351ca,
title = "Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men",
abstract = "AIMS: To examine if (1) there is a positive association between drinking volume in young men and life-time risk of alcohol dependence (AD) and (2) there are other associations between young adulthood factors and life-time risk of AD.DESIGN: Prospective cohort study of sons of fathers with alcohol use disorder (AUD) and matched low-risk controls without paternal AUD. Setting and participants A total of 204 men, who were assessed at baseline in 1979 at age 19-20 years, were followed through record linkage with Danish registers and consecutive psychiatric interviews at the ages of 33, 43 and 53 years.MEASUREMENTS: AD diagnoses were interview-based according to the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition, or made by treating clinicians according to the International Classification of Diseases (ICD) revision 8 (ICD-8) until 1993 and revision 10 (ICD-10) from 1994.We estimated odds ratios (ORs) with 95% confidence intervals (CI) for the development of AD after adjustment for confounders including smoking, social status and paternal AUD.FINDINGS: The following variables from the examination at age 19-20 independently predicted life-time AD: alcohol consumption > 21 beverages/week versus 0-21 [odds ratio (OR) = 2.46, 95% confidence interval (CI) = 1.22-4.97], police contact (OR = 2.60, 95% CI = 1.28-5.28) and institutionalization related to the individual (OR = 2.90, 95% CI = 1.39-6.02). Compared with < 1 beverages/week, the risk for AD did not increase significantly for drinking volume categories: 1-7, 8-14 or 15-21 beverages/week.CONCLUSION: Independently of other risk factors in young adulthood, young Danish men's risk for life-time alcohol dependence appears to be predicted by a drinking volume at age 19-20 years exceeding 21 beverages per week.",
author = "S{\o}rensen, {Holger J} and Ann Manzardo and Emilie Just-{\O}stergaard and Penick, {Elizabeth C} and Becker, {Ulrik M D} and Mortensen, {Erik Lykke} and Joachim Knop",
note = "{\textcopyright} 2020 Society for the Study of Addiction.",
year = "2021",
doi = "10.1111/add.15209",
language = "English",
volume = "116",
pages = "780--787",
journal = "Addiction",
issn = "0965-2140",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Young adult predictors of alcohol dependence to age 53

T2 - a 44-year prospective cohort study of Danish men

AU - Sørensen, Holger J

AU - Manzardo, Ann

AU - Just-Østergaard, Emilie

AU - Penick, Elizabeth C

AU - Becker, Ulrik M D

AU - Mortensen, Erik Lykke

AU - Knop, Joachim

N1 - © 2020 Society for the Study of Addiction.

PY - 2021

Y1 - 2021

N2 - AIMS: To examine if (1) there is a positive association between drinking volume in young men and life-time risk of alcohol dependence (AD) and (2) there are other associations between young adulthood factors and life-time risk of AD.DESIGN: Prospective cohort study of sons of fathers with alcohol use disorder (AUD) and matched low-risk controls without paternal AUD. Setting and participants A total of 204 men, who were assessed at baseline in 1979 at age 19-20 years, were followed through record linkage with Danish registers and consecutive psychiatric interviews at the ages of 33, 43 and 53 years.MEASUREMENTS: AD diagnoses were interview-based according to the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition, or made by treating clinicians according to the International Classification of Diseases (ICD) revision 8 (ICD-8) until 1993 and revision 10 (ICD-10) from 1994.We estimated odds ratios (ORs) with 95% confidence intervals (CI) for the development of AD after adjustment for confounders including smoking, social status and paternal AUD.FINDINGS: The following variables from the examination at age 19-20 independently predicted life-time AD: alcohol consumption > 21 beverages/week versus 0-21 [odds ratio (OR) = 2.46, 95% confidence interval (CI) = 1.22-4.97], police contact (OR = 2.60, 95% CI = 1.28-5.28) and institutionalization related to the individual (OR = 2.90, 95% CI = 1.39-6.02). Compared with < 1 beverages/week, the risk for AD did not increase significantly for drinking volume categories: 1-7, 8-14 or 15-21 beverages/week.CONCLUSION: Independently of other risk factors in young adulthood, young Danish men's risk for life-time alcohol dependence appears to be predicted by a drinking volume at age 19-20 years exceeding 21 beverages per week.

AB - AIMS: To examine if (1) there is a positive association between drinking volume in young men and life-time risk of alcohol dependence (AD) and (2) there are other associations between young adulthood factors and life-time risk of AD.DESIGN: Prospective cohort study of sons of fathers with alcohol use disorder (AUD) and matched low-risk controls without paternal AUD. Setting and participants A total of 204 men, who were assessed at baseline in 1979 at age 19-20 years, were followed through record linkage with Danish registers and consecutive psychiatric interviews at the ages of 33, 43 and 53 years.MEASUREMENTS: AD diagnoses were interview-based according to the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition, or made by treating clinicians according to the International Classification of Diseases (ICD) revision 8 (ICD-8) until 1993 and revision 10 (ICD-10) from 1994.We estimated odds ratios (ORs) with 95% confidence intervals (CI) for the development of AD after adjustment for confounders including smoking, social status and paternal AUD.FINDINGS: The following variables from the examination at age 19-20 independently predicted life-time AD: alcohol consumption > 21 beverages/week versus 0-21 [odds ratio (OR) = 2.46, 95% confidence interval (CI) = 1.22-4.97], police contact (OR = 2.60, 95% CI = 1.28-5.28) and institutionalization related to the individual (OR = 2.90, 95% CI = 1.39-6.02). Compared with < 1 beverages/week, the risk for AD did not increase significantly for drinking volume categories: 1-7, 8-14 or 15-21 beverages/week.CONCLUSION: Independently of other risk factors in young adulthood, young Danish men's risk for life-time alcohol dependence appears to be predicted by a drinking volume at age 19-20 years exceeding 21 beverages per week.

U2 - 10.1111/add.15209

DO - 10.1111/add.15209

M3 - Journal article

C2 - 32710461

VL - 116

SP - 780

EP - 787

JO - Addiction

JF - Addiction

SN - 0965-2140

IS - 4

ER -

ID: 247951896