Visualization of pathogenicity regions in bacteria
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Visualization of pathogenicity regions in bacteria. / Jensen, L J; Friis, C; Ussery, David.
In: Genetica, Vol. 108, No. 1, 2000, p. 47-51.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Visualization of pathogenicity regions in bacteria
AU - Jensen, L J
AU - Friis, C
AU - Ussery, David
PY - 2000
Y1 - 2000
N2 - We show here how pathogenicity islands can be analysed using GenomeAtlases, which is a method for visualising repeats, DNA structural characteristics, and base composition of chromosomes and plasmids. We have applied this method to the E. coli plasmid pO157, and the Y. pestis plasmid pPCP1. In both cases pathogenic genes were shown to differ in A + T content and structural properties. Furthermore, examination of an antibiotic resistance gene cluster from S. typhimurium showed that the same was true for genes encoding antibiotic resistance.
AB - We show here how pathogenicity islands can be analysed using GenomeAtlases, which is a method for visualising repeats, DNA structural characteristics, and base composition of chromosomes and plasmids. We have applied this method to the E. coli plasmid pO157, and the Y. pestis plasmid pPCP1. In both cases pathogenic genes were shown to differ in A + T content and structural properties. Furthermore, examination of an antibiotic resistance gene cluster from S. typhimurium showed that the same was true for genes encoding antibiotic resistance.
M3 - Journal article
C2 - 11145420
VL - 108
SP - 47
EP - 51
JO - Genetica
JF - Genetica
SN - 0016-6707
IS - 1
ER -
ID: 40749937