TY - JOUR

T1 - Variations in reporting of outcomes in randomized trials on diet and physical activity in pregnancy

T2 - A systematic review

AU - Rogozińska, Ewelina

AU - Marlin, Nadine

AU - Yang, Fen

AU - Dodd, Jodie M

AU - Guelfi, Kym

AU - Teede, Helena

AU - Surita, Fernanda

AU - Jensen, Dorte M

AU - Geiker, Nina Rica Wium

AU - Astrup, Arne

AU - Yeo, SeonAe

AU - Kinnunen, Tarja I

AU - Stafne, Signe Nilssen

AU - Cecatti, Jose Guilherme

AU - Bogaerts, Annick

AU - Hauner, Hans

AU - Mol, Ben Willem J

AU - Scudeller, Tânia T

AU - Vinter, Christina A

AU - Renault, Kristina Martha

AU - Devlieger, Roland

AU - Thangaratinam, Shakila

AU - Khan, Khalid S

AU - i-WIP (International Weight Management in Pregnancy) Collaborative Group

N1 - CURIS 2017 NEXS 172

PY - 2017

Y1 - 2017

N2 - Aim: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy.Methods: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes. We defined the quality of reporting as a proportion using a six-item questionnaire. Regression analysis was used to identify factors affecting this quality.Results: Sixty-six randomized controlled trials were published in 78 papers (66 main, 12 secondary). Gestational diabetes (57.6%, 38/66), preterm birth (48.5%, 32/66) and cesarian section (60.6%, 40/66), were the commonly reported 'critically important' outcomes. Gestational weight gain (84.5%, 56/66) and birth weight (87.9%, 58/66) were reported in most papers, although not considered critically important. The median quality of reporting was 0.60 (interquartile range 0.25, 0.83) for a maximum score of one. Study and journal characteristics did not affect quality.Conclusion: Many studies on lifestyle interventions in pregnancy do not report critically important outcomes, highlighting the need for core outcome set development.

AB - Aim: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy.Methods: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes. We defined the quality of reporting as a proportion using a six-item questionnaire. Regression analysis was used to identify factors affecting this quality.Results: Sixty-six randomized controlled trials were published in 78 papers (66 main, 12 secondary). Gestational diabetes (57.6%, 38/66), preterm birth (48.5%, 32/66) and cesarian section (60.6%, 40/66), were the commonly reported 'critically important' outcomes. Gestational weight gain (84.5%, 56/66) and birth weight (87.9%, 58/66) were reported in most papers, although not considered critically important. The median quality of reporting was 0.60 (interquartile range 0.25, 0.83) for a maximum score of one. Study and journal characteristics did not affect quality.Conclusion: Many studies on lifestyle interventions in pregnancy do not report critically important outcomes, highlighting the need for core outcome set development.

KW - Diet

KW - Outcome

KW - Physical activity

KW - Pregnancy

KW - Quality

KW - Randomized trial

U2 - 10.1111/jog.13338

DO - 10.1111/jog.13338

M3 - Review

C2 - 28613023

VL - 43

SP - 1101

EP - 1110

JO - Journal of Obstetrics and Gynaecology Research

JF - Journal of Obstetrics and Gynaecology Research

SN - 1341-8076

IS - 7

ER -