Utility of blood procalcitonin concentration in the management of cancer patients with infections

Research output: Contribution to journalReviewResearchpeer-review

  • Bonita Durnas
  • Marzena Watek
  • Tomasz Wollny
  • Katarzyna Niemirowicz
  • Marzec, Michal Tomasz
  • Robert Bucki
  • Stanislaw Gozdz
Diagnosis of infections in cancer patients is usually problematic since differentiating between infection and fever of unknown origin is often a considerable clinical challenge. In general, increase concentration of blood procalcitonin (PCT) is associated with severe bacterial infection. PCT with an optimal cutoff level of 0.5 ng/mL seems to be the most helpful biochemical parameter in detecting severe infections, mainly bloodstream infection, in patients with hematological cancers. In all clinical situations, the elevated level of PCT should be carefully analyzed, always with a thorough physical examination and an appropriate microbiological assessment.
Original languageEnglish
JournalOncoTargets and Therapy
Volume9
Pages (from-to)469-475
ISSN1178-6930
DOIs
Publication statusPublished - 2016
Externally publishedYes

    Research areas

  • procalcitonin, cancer, infection

ID: 179649529