Typing of 111 ancestry informative markers in an Albanian population

Research output: Contribution to journalConference articleResearchpeer-review

  • EUROFORGEN-NoE

Genetically based prediction of ancestry has a great potential in forensic genetics and may be used as an investigative lead in crime case work or missing person identification.The EUROFORGEN-NoE consortium developed four PCR and SBE multiplexes for typing of 111 ancestry informative markers (AIMs) with the purpose of differentiating Middle Eastern populations from those of the rest of the world (publication in preparation). Before these multiplexes can be applied in forensic case work, population data for these markers are needed.In this work, samples from 51 Albanian individuals were typed with the AIMs set and, at the same time, the performance of each SNP assay was evaluated. After PCR and SBE, samples were typed using the Sequenom MassARRAY®. All samples were typed at least two times. The mass spectra were analyzed using Typer 4 and the genotype calls were further analyzed with a custom designed script in the software R.The results were compared to other population samples previously typed for the same markers. The panel of AIMs was capable of differentiating the Albanian population from other population groups except for the Greek population. These results were expected due to the history and the geographical proximity of Albania and Greece.

Original languageEnglish
JournalForensic Science International: Genetics Supplement Series
Volume5
Pages (from-to)e124-e125
Number of pages2
ISSN1875-1768
DOIs
Publication statusPublished - 28 Dec 2015
Event26th Congress of the International Society of Forensic Genetics - Krakow, Poland
Duration: 31 Aug 20155 Sep 2015

Conference

Conference26th Congress of the International Society of Forensic Genetics
CountryPoland
CityKrakow
Period31/08/201505/09/2015

    Research areas

  • AIMs, Albania, EUROFORGEN-NoE, Population genetics

ID: 152268765