Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study

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Trends in antidepressant use among children and adolescents : a Scandinavian drug utilization study. / Wesselhoeft, R; Jensen, P B; Talati, A; Reutfors, J; Furu, K; Strandberg-Larsen, K; Damkier, P; Pottegård, A; Bliddal, M.

In: Acta Psychiatrica Scandinavica, Vol. 141, No. 1, 2020, p. 34-42.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Wesselhoeft, R, Jensen, PB, Talati, A, Reutfors, J, Furu, K, Strandberg-Larsen, K, Damkier, P, Pottegård, A & Bliddal, M 2020, 'Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study', Acta Psychiatrica Scandinavica, vol. 141, no. 1, pp. 34-42. https://doi.org/10.1111/acps.13116

APA

Wesselhoeft, R., Jensen, P. B., Talati, A., Reutfors, J., Furu, K., Strandberg-Larsen, K., Damkier, P., Pottegård, A., & Bliddal, M. (2020). Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study. Acta Psychiatrica Scandinavica, 141(1), 34-42. https://doi.org/10.1111/acps.13116

Vancouver

Wesselhoeft R, Jensen PB, Talati A, Reutfors J, Furu K, Strandberg-Larsen K et al. Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study. Acta Psychiatrica Scandinavica. 2020;141(1):34-42. https://doi.org/10.1111/acps.13116

Author

Wesselhoeft, R ; Jensen, P B ; Talati, A ; Reutfors, J ; Furu, K ; Strandberg-Larsen, K ; Damkier, P ; Pottegård, A ; Bliddal, M. / Trends in antidepressant use among children and adolescents : a Scandinavian drug utilization study. In: Acta Psychiatrica Scandinavica. 2020 ; Vol. 141, No. 1. pp. 34-42.

Bibtex

@article{84d1e8440ebd40889931a588b1e4d0ea,
title = "Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study",
abstract = "OBJECTIVE: To compare antidepressant utilization in individuals aged 5-19 years from the Scandinavian countries.METHODS: A population-based drug utilization study using publicly available data of antidepressant use from Denmark, Norway, and Sweden.RESULTS: In the study period from 2007 to 2017, the proportion of antidepressant users increased markedly in Sweden (9.3-18.0/1000) compared to Norway (5.1-7.6/1000) and Denmark (9.3-7.5/1000). In 2017, the cumulated defined daily doses (DDD) of selective serotonin reuptake inhibitors were 5611/1000 inhabitants in Sweden, 2709/1000 in Denmark, and 1848/1000 in Norway. The use of 'other antidepressants' (ATC code N06AX) also increased in Sweden with a higher DDD in 2017 (497/1000) compared to Denmark (225/1000) and Norway (170/1000). The use of tricyclic antidepressants was generally low in 2017 with DDDs ranging between 30-42 per 1000. The proportion of antidepressant users was highest among 15- to 19-year-old individuals. Girls were more likely to receive treatment than boys, and the treated female/male ratios per 1000 were similar in Sweden (2.39), Denmark (2.44), and Norway (2.63).CONCLUSION: Even in highly comparable healthcare systems like the Scandinavian countries', variation in antidepressant use is considerable. Swedish children and adolescents have a markedly higher and still increasing use of antidepressants compared to Danish and Norwegian peers.",
keywords = "Adolescent, Age Factors, Antidepressive Agents/therapeutic use, Antidepressive Agents, Tricyclic/therapeutic use, Child, Child, Preschool, Denmark, Drug Labeling/statistics & numerical data, Drug Utilization/trends, Female, Humans, Male, Norway, Scandinavian and Nordic Countries, Serotonin Uptake Inhibitors/therapeutic use, Sex Factors, Sweden, Young Adult",
author = "R Wesselhoeft and Jensen, {P B} and A Talati and J Reutfors and K Furu and K Strandberg-Larsen and P Damkier and A Potteg{\aa}rd and M Bliddal",
note = "{\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2020",
doi = "10.1111/acps.13116",
language = "English",
volume = "141",
pages = "34--42",
journal = "Acta Psychiatrica Scandinavica",
issn = "0001-690X",
publisher = "Wiley",
number = "1",

}

RIS

TY - JOUR

T1 - Trends in antidepressant use among children and adolescents

T2 - a Scandinavian drug utilization study

AU - Wesselhoeft, R

AU - Jensen, P B

AU - Talati, A

AU - Reutfors, J

AU - Furu, K

AU - Strandberg-Larsen, K

AU - Damkier, P

AU - Pottegård, A

AU - Bliddal, M

N1 - © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2020

Y1 - 2020

N2 - OBJECTIVE: To compare antidepressant utilization in individuals aged 5-19 years from the Scandinavian countries.METHODS: A population-based drug utilization study using publicly available data of antidepressant use from Denmark, Norway, and Sweden.RESULTS: In the study period from 2007 to 2017, the proportion of antidepressant users increased markedly in Sweden (9.3-18.0/1000) compared to Norway (5.1-7.6/1000) and Denmark (9.3-7.5/1000). In 2017, the cumulated defined daily doses (DDD) of selective serotonin reuptake inhibitors were 5611/1000 inhabitants in Sweden, 2709/1000 in Denmark, and 1848/1000 in Norway. The use of 'other antidepressants' (ATC code N06AX) also increased in Sweden with a higher DDD in 2017 (497/1000) compared to Denmark (225/1000) and Norway (170/1000). The use of tricyclic antidepressants was generally low in 2017 with DDDs ranging between 30-42 per 1000. The proportion of antidepressant users was highest among 15- to 19-year-old individuals. Girls were more likely to receive treatment than boys, and the treated female/male ratios per 1000 were similar in Sweden (2.39), Denmark (2.44), and Norway (2.63).CONCLUSION: Even in highly comparable healthcare systems like the Scandinavian countries', variation in antidepressant use is considerable. Swedish children and adolescents have a markedly higher and still increasing use of antidepressants compared to Danish and Norwegian peers.

AB - OBJECTIVE: To compare antidepressant utilization in individuals aged 5-19 years from the Scandinavian countries.METHODS: A population-based drug utilization study using publicly available data of antidepressant use from Denmark, Norway, and Sweden.RESULTS: In the study period from 2007 to 2017, the proportion of antidepressant users increased markedly in Sweden (9.3-18.0/1000) compared to Norway (5.1-7.6/1000) and Denmark (9.3-7.5/1000). In 2017, the cumulated defined daily doses (DDD) of selective serotonin reuptake inhibitors were 5611/1000 inhabitants in Sweden, 2709/1000 in Denmark, and 1848/1000 in Norway. The use of 'other antidepressants' (ATC code N06AX) also increased in Sweden with a higher DDD in 2017 (497/1000) compared to Denmark (225/1000) and Norway (170/1000). The use of tricyclic antidepressants was generally low in 2017 with DDDs ranging between 30-42 per 1000. The proportion of antidepressant users was highest among 15- to 19-year-old individuals. Girls were more likely to receive treatment than boys, and the treated female/male ratios per 1000 were similar in Sweden (2.39), Denmark (2.44), and Norway (2.63).CONCLUSION: Even in highly comparable healthcare systems like the Scandinavian countries', variation in antidepressant use is considerable. Swedish children and adolescents have a markedly higher and still increasing use of antidepressants compared to Danish and Norwegian peers.

KW - Adolescent

KW - Age Factors

KW - Antidepressive Agents/therapeutic use

KW - Antidepressive Agents, Tricyclic/therapeutic use

KW - Child

KW - Child, Preschool

KW - Denmark

KW - Drug Labeling/statistics & numerical data

KW - Drug Utilization/trends

KW - Female

KW - Humans

KW - Male

KW - Norway

KW - Scandinavian and Nordic Countries

KW - Serotonin Uptake Inhibitors/therapeutic use

KW - Sex Factors

KW - Sweden

KW - Young Adult

U2 - 10.1111/acps.13116

DO - 10.1111/acps.13116

M3 - Journal article

C2 - 31618447

VL - 141

SP - 34

EP - 42

JO - Acta Psychiatrica Scandinavica

JF - Acta Psychiatrica Scandinavica

SN - 0001-690X

IS - 1

ER -

ID: 259673102