Transit-time analysis of contrast agent in the liver: Advantages of contrast harmonic imaging compared with spectral Doppler quantification

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The aim of the study was to examine if a pulse inversion technique, contrast harmonic imaging (CHI), could assess the arrival of Levovist in hepatic veins (transit-time), and to describe possible advantages over a previously described method with spectral Doppler quantification. Twelve patients were scanned using CHI after intravenous bolus-injection, the arrival was seen as white reflections in the hepatic veins. In patients with cirrhosis (n = 2) transit-time was 13 seconds, non-cirrhotic diffuse liver disease (n = 3) median 17 (range, 12-22), focal liver lesions (n = 7) median 24 (range, 16-27). Bolus-injection was repeated in five patients and transit-time assessed by spectral Doppler analysis: In four patients the two methods gave transit-times within 2 seconds apart, in one patient 5 seconds apart. In conclusion, it is possible to assess transit-time using CHI. The method is simpler than a previously described method which require computer analysis. Also, several hepatic veins can be assessed simultaneously.

Original languageEnglish
JournalUltrasound in Medicine and Biology
Issue numberSUPPL. 2
Pages (from-to)A140
Publication statusPublished - 2000
EventThe 9th Congress of World Federation for Ultrasound in Medicine and Biology - Florence, Italy
Duration: 6 May 200010 May 2000


ConferenceThe 9th Congress of World Federation for Ultrasound in Medicine and Biology
CityFlorence, Italy

ID: 331495121