The HETE Is on FFAR1 and Pancreatic Islet Cells
Research output: Contribution to journal › Journal article › Research › peer-review
It is known but generally unappreciated that the fatty acid receptor FFAR1 (GPR40) is responsible for a major part of glucose-induced insulin secretion. This puzzling fact is now explained by Tunaru et al. (2018), who demonstrate that glucose-induced 20-hydroxyeicosatetraenoic acid (20-HETE) amplifies insulin secretion through autocrine activation of FFAR1.
| Original language | English |
|---|---|
| Journal | Cell Metabolism |
| Volume | 27 |
| Issue number | 2 |
| Pages (from-to) | 273-275 |
| Number of pages | 3 |
| ISSN | 1550-4131 |
| DOIs | |
| Publication status | Published - 2018 |
- Journal Article
Research areas
ID: 189764824