The computer as a laboratory for the physical chemistry of membranes

Research output: Contribution to journalJournal articlepeer-review

Standard

The computer as a laboratory for the physical chemistry of membranes. / Mouritsen, O. G.; Dammann, B.; Fogedby, H. C.; Ipsen, J. H.; Jeppesen, C.; Jørgensen, K.; Risbo, J.; Sabra, M. C.; Sperotto, M. M.; Zuckermann, M. J.

In: Biophysical Chemistry, Vol. 55, No. 1-2, 1995, p. 55-68.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Mouritsen, OG, Dammann, B, Fogedby, HC, Ipsen, JH, Jeppesen, C, Jørgensen, K, Risbo, J, Sabra, MC, Sperotto, MM & Zuckermann, MJ 1995, 'The computer as a laboratory for the physical chemistry of membranes', Biophysical Chemistry, vol. 55, no. 1-2, pp. 55-68. https://doi.org/10.1016/0301-4622(94)00142-7

APA

Mouritsen, O. G., Dammann, B., Fogedby, H. C., Ipsen, J. H., Jeppesen, C., Jørgensen, K., Risbo, J., Sabra, M. C., Sperotto, M. M., & Zuckermann, M. J. (1995). The computer as a laboratory for the physical chemistry of membranes. Biophysical Chemistry, 55(1-2), 55-68. https://doi.org/10.1016/0301-4622(94)00142-7

Vancouver

Mouritsen OG, Dammann B, Fogedby HC, Ipsen JH, Jeppesen C, Jørgensen K et al. The computer as a laboratory for the physical chemistry of membranes. Biophysical Chemistry. 1995;55(1-2):55-68. https://doi.org/10.1016/0301-4622(94)00142-7

Author

Mouritsen, O. G. ; Dammann, B. ; Fogedby, H. C. ; Ipsen, J. H. ; Jeppesen, C. ; Jørgensen, K. ; Risbo, J. ; Sabra, M. C. ; Sperotto, M. M. ; Zuckermann, M. J. / The computer as a laboratory for the physical chemistry of membranes. In: Biophysical Chemistry. 1995 ; Vol. 55, No. 1-2. pp. 55-68.

Bibtex

@article{170a69d5d0d24031bceff4f44cbd938e,
title = "The computer as a laboratory for the physical chemistry of membranes",
abstract = "A mini-review is given of some recent advances in the use of computer-simulation approaches to the study of physico-chemical properties of lipid bilayers and biological membranes. The simulations are based on microscopic molecular interaction models as well as random-surface models of fluid membranes. Particular emphasis is put on those properties that are controlled by the many-particle character of the lamellar membrane, i.e. correlations and fluctuations in density, composition and large-scale conformational structure. It is discussed how dynamic membrane heterogeneity arises and how it is affected by various molecular species interacting with membranes, such as cholesterol, drugs, insecticides, as well as polypeptides and integral membrane proteins. The influence of bending rigidity and osmotic-pressure gradients on large-scale membrane conformation and topology is described.",
keywords = "Bending rigidity, Cholesterol, Computer simulation, Dynamic heterogeneity, Fluctuation, Insecticide, Lipid bilayer, Lipid mixture, Lipid-protein interaction, Membrane topology, Phase separation, Phase transition, Random surface",
author = "Mouritsen, {O. G.} and B. Dammann and Fogedby, {H. C.} and Ipsen, {J. H.} and C. Jeppesen and K. J{\o}rgensen and J. Risbo and Sabra, {M. C.} and Sperotto, {M. M.} and Zuckermann, {M. J.}",
year = "1995",
doi = "10.1016/0301-4622(94)00142-7",
language = "English",
volume = "55",
pages = "55--68",
journal = "Biophysical Chemistry",
issn = "0301-4622",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - The computer as a laboratory for the physical chemistry of membranes

AU - Mouritsen, O. G.

AU - Dammann, B.

AU - Fogedby, H. C.

AU - Ipsen, J. H.

AU - Jeppesen, C.

AU - Jørgensen, K.

AU - Risbo, J.

AU - Sabra, M. C.

AU - Sperotto, M. M.

AU - Zuckermann, M. J.

PY - 1995

Y1 - 1995

N2 - A mini-review is given of some recent advances in the use of computer-simulation approaches to the study of physico-chemical properties of lipid bilayers and biological membranes. The simulations are based on microscopic molecular interaction models as well as random-surface models of fluid membranes. Particular emphasis is put on those properties that are controlled by the many-particle character of the lamellar membrane, i.e. correlations and fluctuations in density, composition and large-scale conformational structure. It is discussed how dynamic membrane heterogeneity arises and how it is affected by various molecular species interacting with membranes, such as cholesterol, drugs, insecticides, as well as polypeptides and integral membrane proteins. The influence of bending rigidity and osmotic-pressure gradients on large-scale membrane conformation and topology is described.

AB - A mini-review is given of some recent advances in the use of computer-simulation approaches to the study of physico-chemical properties of lipid bilayers and biological membranes. The simulations are based on microscopic molecular interaction models as well as random-surface models of fluid membranes. Particular emphasis is put on those properties that are controlled by the many-particle character of the lamellar membrane, i.e. correlations and fluctuations in density, composition and large-scale conformational structure. It is discussed how dynamic membrane heterogeneity arises and how it is affected by various molecular species interacting with membranes, such as cholesterol, drugs, insecticides, as well as polypeptides and integral membrane proteins. The influence of bending rigidity and osmotic-pressure gradients on large-scale membrane conformation and topology is described.

KW - Bending rigidity

KW - Cholesterol

KW - Computer simulation

KW - Dynamic heterogeneity

KW - Fluctuation

KW - Insecticide

KW - Lipid bilayer

KW - Lipid mixture

KW - Lipid-protein interaction

KW - Membrane topology

KW - Phase separation

KW - Phase transition

KW - Random surface

U2 - 10.1016/0301-4622(94)00142-7

DO - 10.1016/0301-4622(94)00142-7

M3 - Journal article

AN - SCOPUS:0029026515

VL - 55

SP - 55

EP - 68

JO - Biophysical Chemistry

JF - Biophysical Chemistry

SN - 0301-4622

IS - 1-2

ER -

ID: 236889021