TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis

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TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis. / Schmidt, Esben Gjerløff Wedebye; Larsen, Hjalte List; Kristensen, Nanna Ny; Poulsen, Steen Seier; Pedersen, Anne Marie Lynge; Claesson, Mogens Helweg; Pedersen, Anders Elm.

In: Inflammatory Bowel Diseases, Vol. 19, No. 8, 2013, p. 1567-1576.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Schmidt, EGW, Larsen, HL, Kristensen, NN, Poulsen, SS, Pedersen, AML, Claesson, MH & Pedersen, AE 2013, 'TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis', Inflammatory Bowel Diseases, vol. 19, no. 8, pp. 1567-1576. https://doi.org/10.1097/MIB.0b013e318286fa1c

APA

Schmidt, E. G. W., Larsen, H. L., Kristensen, N. N., Poulsen, S. S., Pedersen, A. M. L., Claesson, M. H., & Pedersen, A. E. (2013). TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis. Inflammatory Bowel Diseases, 19(8), 1567-1576. https://doi.org/10.1097/MIB.0b013e318286fa1c

Vancouver

Schmidt EGW, Larsen HL, Kristensen NN, Poulsen SS, Pedersen AML, Claesson MH et al. TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis. Inflammatory Bowel Diseases. 2013;19(8):1567-1576. https://doi.org/10.1097/MIB.0b013e318286fa1c

Author

Schmidt, Esben Gjerløff Wedebye ; Larsen, Hjalte List ; Kristensen, Nanna Ny ; Poulsen, Steen Seier ; Pedersen, Anne Marie Lynge ; Claesson, Mogens Helweg ; Pedersen, Anders Elm. / TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis. In: Inflammatory Bowel Diseases. 2013 ; Vol. 19, No. 8. pp. 1567-1576.

Bibtex

@article{055d6cd65ead4e8096b1d7c5927b96d2,

title = "TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis",

abstract = "T helper (TH) 17 cells are believed to play a pivotal role in development of inflammatory bowel disease, and their contribution to intestinal inflammation has been studied in various models of colitis. TH17 cells produce a range of cytokines, some of which are potential targets for immunotherapy. However, blockade of IL-17A alone with secukinumab was not effective in Crohn's disease. In this regard, the pathogenic impact of IL-17A versus IL-17F during intestinal inflammation is still unresolved.",

author = "Schmidt, {Esben Gjerl{\o}ff Wedebye} and Larsen, {Hjalte List} and Kristensen, {Nanna Ny} and Poulsen, {Steen Seier} and Pedersen, {Anne Marie Lynge} and Claesson, {Mogens Helweg} and Pedersen, {Anders Elm}",

year = "2013",

doi = "10.1097/MIB.0b013e318286fa1c",

language = "English",

volume = "19",

pages = "1567--1576",

journal = "Inflammatory Bowel Diseases",

issn = "1078-0998",

publisher = "Lippincott Williams & Wilkins",

number = "8",

}

RIS

TY - JOUR

T1 - TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis

AU - Schmidt, Esben Gjerløff Wedebye

AU - Larsen, Hjalte List

AU - Kristensen, Nanna Ny

AU - Poulsen, Steen Seier

AU - Pedersen, Anne Marie Lynge

AU - Claesson, Mogens Helweg

AU - Pedersen, Anders Elm

PY - 2013

Y1 - 2013

N2 - T helper (TH) 17 cells are believed to play a pivotal role in development of inflammatory bowel disease, and their contribution to intestinal inflammation has been studied in various models of colitis. TH17 cells produce a range of cytokines, some of which are potential targets for immunotherapy. However, blockade of IL-17A alone with secukinumab was not effective in Crohn's disease. In this regard, the pathogenic impact of IL-17A versus IL-17F during intestinal inflammation is still unresolved.

AB - T helper (TH) 17 cells are believed to play a pivotal role in development of inflammatory bowel disease, and their contribution to intestinal inflammation has been studied in various models of colitis. TH17 cells produce a range of cytokines, some of which are potential targets for immunotherapy. However, blockade of IL-17A alone with secukinumab was not effective in Crohn's disease. In this regard, the pathogenic impact of IL-17A versus IL-17F during intestinal inflammation is still unresolved.

U2 - 10.1097/MIB.0b013e318286fa1c

DO - 10.1097/MIB.0b013e318286fa1c

M3 - Journal article

C2 - 23689808

VL - 19

SP - 1567

EP - 1576

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

SN - 1078-0998

IS - 8

ER -

ID: 47486081