STITCH 2: an interaction network database for small molecules and proteins

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

STITCH 2: an interaction network database for small molecules and proteins. / Kuhn, Michael; Szklarczyk, Damian; Franceschini, Andrea; Campillos, Monica; von Mering, Christian; Jensen, Lars Juhl; Beyer, Andreas; Bork, Peer.

In: Nucleic Acids Research, Vol. 38, No. Database issue, 2010, p. D552-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kuhn, M, Szklarczyk, D, Franceschini, A, Campillos, M, von Mering, C, Jensen, LJ, Beyer, A & Bork, P 2010, 'STITCH 2: an interaction network database for small molecules and proteins', Nucleic Acids Research, vol. 38, no. Database issue, pp. D552-6. https://doi.org/10.1093/nar/gkp937

APA

Kuhn, M., Szklarczyk, D., Franceschini, A., Campillos, M., von Mering, C., Jensen, L. J., Beyer, A., & Bork, P. (2010). STITCH 2: an interaction network database for small molecules and proteins. Nucleic Acids Research, 38(Database issue), D552-6. https://doi.org/10.1093/nar/gkp937

Vancouver

Kuhn M, Szklarczyk D, Franceschini A, Campillos M, von Mering C, Jensen LJ et al. STITCH 2: an interaction network database for small molecules and proteins. Nucleic Acids Research. 2010;38(Database issue):D552-6. https://doi.org/10.1093/nar/gkp937

Author

Kuhn, Michael ; Szklarczyk, Damian ; Franceschini, Andrea ; Campillos, Monica ; von Mering, Christian ; Jensen, Lars Juhl ; Beyer, Andreas ; Bork, Peer. / STITCH 2: an interaction network database for small molecules and proteins. In: Nucleic Acids Research. 2010 ; Vol. 38, No. Database issue. pp. D552-6.

Bibtex

@article{ff6d5be07dd411df928f000ea68e967b,

title = "STITCH 2: an interaction network database for small molecules and proteins",

abstract = "Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74,000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/.",

author = "Michael Kuhn and Damian Szklarczyk and Andrea Franceschini and Monica Campillos and {von Mering}, Christian and Jensen, {Lars Juhl} and Andreas Beyer and Peer Bork",

note = "Keywords: Animals; Aspirin; Computational Biology; Databases, Protein; Drug Evaluation, Preclinical; Humans; Information Storage and Retrieval; Internet; Models, Chemical; Pharmaceutical Preparations; Protein Interaction Mapping; Proteins; Software; User-Computer Interface",

year = "2010",

doi = "10.1093/nar/gkp937",

language = "English",

volume = "38",

pages = "D552--6",

journal = "Nucleic Acids Research",

issn = "0305-1048",

publisher = "Oxford University Press",

number = "Database issue",

}

RIS

TY - JOUR

T1 - STITCH 2: an interaction network database for small molecules and proteins

AU - Kuhn, Michael

AU - Szklarczyk, Damian

AU - Franceschini, Andrea

AU - Campillos, Monica

AU - von Mering, Christian

AU - Jensen, Lars Juhl

AU - Beyer, Andreas

AU - Bork, Peer

N1 - Keywords: Animals; Aspirin; Computational Biology; Databases, Protein; Drug Evaluation, Preclinical; Humans; Information Storage and Retrieval; Internet; Models, Chemical; Pharmaceutical Preparations; Protein Interaction Mapping; Proteins; Software; User-Computer Interface

PY - 2010

Y1 - 2010

N2 - Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74,000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/.

AB - Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74,000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/.

U2 - 10.1093/nar/gkp937

DO - 10.1093/nar/gkp937

M3 - Journal article

C2 - 19897548

VL - 38

SP - D552-6

JO - Nucleic Acids Research

JF - Nucleic Acids Research

SN - 0305-1048

IS - Database issue

ER -

ID: 20417049