Stigende incidens af morbus Crohn i Københavns Amt
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Stigende incidens af morbus Crohn i Københavns Amt. / Munkholm, P; Langholz, E; Nielsen, O H; Kreiner, S; Binder, V.
In: Ugeskrift for Laeger, Vol. 155, No. 40, 04.10.1993, p. 3199-202.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Stigende incidens af morbus Crohn i Københavns Amt
AU - Munkholm, P
AU - Langholz, E
AU - Nielsen, O H
AU - Kreiner, S
AU - Binder, V
PY - 1993/10/4
Y1 - 1993/10/4
N2 - The incidence of Crohn's disease was assessed in a population based study in Copenhagen County from 1962-1987. The incidence increased six fold during the study period from 0.62/10(5) in 1962 to a mean of 4.1/10(5) from 1979-1987, equally in both sexes. The highest incidence was found in the age group 15-24 years: 12.8/10(5) for women and 6.0/10(5) for men (as mean of the period 1979-1987). The prevalence at the end of the study was 54/10(5). The clinical symptoms and extent of disease at diagnosis did not change over the time, but a significantly higher disease activity was found in the 1980's, 74% (1962-1979) vs 84% (1980-1987), p = 0.04. The increase in incidence of Crohn's disease is well established in most parts of the industrialized world. The analysis shows that it is not due to a new disease entity, since the extent of disease, the age and sex distribution, and the symptoms remained unchanged during the 26 year study period.
AB - The incidence of Crohn's disease was assessed in a population based study in Copenhagen County from 1962-1987. The incidence increased six fold during the study period from 0.62/10(5) in 1962 to a mean of 4.1/10(5) from 1979-1987, equally in both sexes. The highest incidence was found in the age group 15-24 years: 12.8/10(5) for women and 6.0/10(5) for men (as mean of the period 1979-1987). The prevalence at the end of the study was 54/10(5). The clinical symptoms and extent of disease at diagnosis did not change over the time, but a significantly higher disease activity was found in the 1980's, 74% (1962-1979) vs 84% (1980-1987), p = 0.04. The increase in incidence of Crohn's disease is well established in most parts of the industrialized world. The analysis shows that it is not due to a new disease entity, since the extent of disease, the age and sex distribution, and the symptoms remained unchanged during the 26 year study period.
KW - Adolescent
KW - Adult
KW - Aged
KW - Crohn Disease/diagnosis
KW - Denmark/epidemiology
KW - Female
KW - Humans
KW - Incidence
KW - Male
KW - Middle Aged
KW - Registries
M3 - Tidsskriftartikel
C2 - 8236566
VL - 155
SP - 3199
EP - 3202
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 40
ER -
ID: 219531181