Spontaneous low-frequency oscillations in cerebral vessels: applications in carotid artery disease and ischemic stroke
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Spontaneous low-frequency oscillations in cerebral vessels : applications in carotid artery disease and ischemic stroke. / Schytz, Henrik W; Hansson, Andreas; Phillip, Dorte; Selb, Juliette; Boas, David A; Iversen, Helle Klingenberg; Ashina, Messoud.
In: Journal of Stroke & Cerebrovascular Diseases, Vol. 19, No. 6, 2010, p. 465-474.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Spontaneous low-frequency oscillations in cerebral vessels
T2 - applications in carotid artery disease and ischemic stroke
AU - Schytz, Henrik W
AU - Hansson, Andreas
AU - Phillip, Dorte
AU - Selb, Juliette
AU - Boas, David A
AU - Iversen, Helle Klingenberg
AU - Ashina, Messoud
N1 - Copyright © 2010. Published by Elsevier Inc.
PY - 2010
Y1 - 2010
N2 - The etiology behind and physiological significance of spontaneous oscillations in the low-frequency spectrum in both systemic and cerebral vessels remain unknown. Experimental studies have proposed that spontaneous oscillations in cerebral blood flow reflect impaired cerebral autoregulation (CA). Analysis of CA by measurement of spontaneous oscillations in the low-frequency spectrum in cerebral vessels might be a useful tool for assessing risk and investigating different treatment strategies in carotid artery disease (CAD) and stroke. We reviewed studies exploring spontaneous oscillations in the low-frequency spectrum in patients with CAD and ischemic stroke, conditions known to involve impaired CA. Several studies have reported changes in oscillations after CAD and stroke after surgery and over time compared with healthy controls. Phase shift in the frequency domain and correlation coefficients in the time domain are the most frequently used parameters for analyzing spontaneous oscillations in systemic and cerebral vessels. At present, there is no gold standard for analyzing spontaneous oscillations in the low-frequency spectrum, and simplistic models of CA have failed to predict or explain the spontaneous oscillation changes found in CAD and stroke studies. Near-infrared spectroscopy is suggested as a future complementary tool for assessing changes affecting the cortical arterial system.
AB - The etiology behind and physiological significance of spontaneous oscillations in the low-frequency spectrum in both systemic and cerebral vessels remain unknown. Experimental studies have proposed that spontaneous oscillations in cerebral blood flow reflect impaired cerebral autoregulation (CA). Analysis of CA by measurement of spontaneous oscillations in the low-frequency spectrum in cerebral vessels might be a useful tool for assessing risk and investigating different treatment strategies in carotid artery disease (CAD) and stroke. We reviewed studies exploring spontaneous oscillations in the low-frequency spectrum in patients with CAD and ischemic stroke, conditions known to involve impaired CA. Several studies have reported changes in oscillations after CAD and stroke after surgery and over time compared with healthy controls. Phase shift in the frequency domain and correlation coefficients in the time domain are the most frequently used parameters for analyzing spontaneous oscillations in systemic and cerebral vessels. At present, there is no gold standard for analyzing spontaneous oscillations in the low-frequency spectrum, and simplistic models of CA have failed to predict or explain the spontaneous oscillation changes found in CAD and stroke studies. Near-infrared spectroscopy is suggested as a future complementary tool for assessing changes affecting the cortical arterial system.
KW - Brain
KW - Brain Ischemia
KW - Carotid Stenosis
KW - Cerebrovascular Circulation
KW - Homeostasis
KW - Humans
KW - Oscillometry
KW - Spectroscopy, Near-Infrared
KW - Stroke
KW - Time Factors
KW - Ultrasonography, Doppler, Transcranial
U2 - 10.1016/j.jstrokecerebrovasdis.2010.06.001
DO - 10.1016/j.jstrokecerebrovasdis.2010.06.001
M3 - Journal article
C2 - 20864356
VL - 19
SP - 465
EP - 474
JO - Journal of Stroke & Cerebrovascular Diseases
JF - Journal of Stroke & Cerebrovascular Diseases
SN - 1052-3057
IS - 6
ER -
ID: 34085147