Site-selective three-component reaction for dual-functionalization of peptides

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Site-selective three-component reaction for dual-functionalization of peptides. / Munch, Henrik Kofoed; Rasmussen, Jakob Ewald; Popa, Gina; Christensen, Jørn Bolstad; Jensen, K.J.

In: Chemical Communications, Vol. 49, No. 19, 2013, p. 1936-1938.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Munch, HK, Rasmussen, JE, Popa, G, Christensen, JB & Jensen, KJ 2013, 'Site-selective three-component reaction for dual-functionalization of peptides', Chemical Communications, vol. 49, no. 19, pp. 1936-1938. https://doi.org/10.1039/c3cc38673b

APA

Munch, H. K., Rasmussen, J. E., Popa, G., Christensen, J. B., & Jensen, K. J. (2013). Site-selective three-component reaction for dual-functionalization of peptides. Chemical Communications, 49(19), 1936-1938. https://doi.org/10.1039/c3cc38673b

Vancouver

Munch HK, Rasmussen JE, Popa G, Christensen JB, Jensen KJ. Site-selective three-component reaction for dual-functionalization of peptides. Chemical Communications. 2013;49(19):1936-1938. https://doi.org/10.1039/c3cc38673b

Author

Munch, Henrik Kofoed ; Rasmussen, Jakob Ewald ; Popa, Gina ; Christensen, Jørn Bolstad ; Jensen, K.J. / Site-selective three-component reaction for dual-functionalization of peptides. In: Chemical Communications. 2013 ; Vol. 49, No. 19. pp. 1936-1938.

Bibtex

@article{0d660a4296a042d599554a70eb808995,
title = "Site-selective three-component reaction for dual-functionalization of peptides",
abstract = "A site-selective dual-functionalization of peptides is presented, involving readily available maleimides as well as N-hydroxylamines. The modification proceeds through a three component 1,3-dipolar cycloaddition, forming a stable product. This was exemplified by the one-pot attachment of two molecular imaging moieties to a tumor binding cyclic peptide, and was extended to the conjugation of a DOTA chelator to a 12 kDa protein.",
author = "Munch, {Henrik Kofoed} and Rasmussen, {Jakob Ewald} and Gina Popa and Christensen, {J{\o}rn Bolstad} and K.J. Jensen",
year = "2013",
doi = "10.1039/c3cc38673b",
language = "English",
volume = "49",
pages = "1936--1938",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "19",

}

RIS

TY - JOUR

T1 - Site-selective three-component reaction for dual-functionalization of peptides

AU - Munch, Henrik Kofoed

AU - Rasmussen, Jakob Ewald

AU - Popa, Gina

AU - Christensen, Jørn Bolstad

AU - Jensen, K.J.

PY - 2013

Y1 - 2013

N2 - A site-selective dual-functionalization of peptides is presented, involving readily available maleimides as well as N-hydroxylamines. The modification proceeds through a three component 1,3-dipolar cycloaddition, forming a stable product. This was exemplified by the one-pot attachment of two molecular imaging moieties to a tumor binding cyclic peptide, and was extended to the conjugation of a DOTA chelator to a 12 kDa protein.

AB - A site-selective dual-functionalization of peptides is presented, involving readily available maleimides as well as N-hydroxylamines. The modification proceeds through a three component 1,3-dipolar cycloaddition, forming a stable product. This was exemplified by the one-pot attachment of two molecular imaging moieties to a tumor binding cyclic peptide, and was extended to the conjugation of a DOTA chelator to a 12 kDa protein.

UR - http://www.scopus.com/inward/record.url?scp=84873673638&partnerID=8YFLogxK

U2 - 10.1039/c3cc38673b

DO - 10.1039/c3cc38673b

M3 - Journal article

C2 - 23370690

AN - SCOPUS:84873673638

VL - 49

SP - 1936

EP - 1938

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 19

ER -

ID: 88717747