Reversibility of the effects on local circulation of high lipid concentrations in blood

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Reversibility of the effects on local circulation of high lipid concentrations in blood. / Bülow, J; Madsen, J; Højgaard, L.

In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement, Vol. 50, No. 3, 05.1990, p. 291-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bülow, J, Madsen, J & Højgaard, L 1990, 'Reversibility of the effects on local circulation of high lipid concentrations in blood', Scandinavian Journal of Clinical and Laboratory Investigation. Supplement, vol. 50, no. 3, pp. 291-6.

APA

Bülow, J., Madsen, J., & Højgaard, L. (1990). Reversibility of the effects on local circulation of high lipid concentrations in blood. Scandinavian Journal of Clinical and Laboratory Investigation. Supplement, 50(3), 291-6.

Vancouver

Bülow J, Madsen J, Højgaard L. Reversibility of the effects on local circulation of high lipid concentrations in blood. Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 1990 May;50(3):291-6.

Author

Bülow, J ; Madsen, J ; Højgaard, L. / Reversibility of the effects on local circulation of high lipid concentrations in blood. In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 1990 ; Vol. 50, No. 3. pp. 291-6.

Bibtex

@article{f501bc3353684d1884f6e509844db300,
title = "Reversibility of the effects on local circulation of high lipid concentrations in blood",
abstract = "Regional perfusion and vascular resistance were examined in different tissues with the radioactive microsphere technique in G{\"o}ttingen minipigs before, during and after treatment with Intralipid and heparin. This treatment led to an increase in the free fatty acid/albumin molar ratio from 0.39 +/- 0.23 to 3.43 +/- 1.37. Concomitantly a decrease in regional perfusion and an increase in regional vascular resistance was found in skin, adipose tissue, skeletal muscle, kidney, the gastro-intestinal tract, the thyroid and pancreas, while heart and liver showed vasodilatation. The vascular effects were fully reversible when the free fatty acid/albumin molar ratio had normalized. This vascular effect of lipid emulsions has to be considered when patients are treated with parenteral nutrition.",
keywords = "Adipose Tissue, Animals, Bone and Bones, Coronary Circulation, Digestive System, Fat Emulsions, Intravenous, Fatty Acids, Nonesterified, Female, Heparin, Kidney, Lipids, Liver, Muscles, Pancreas, Serum Albumin, Skin, Swine, Swine, Miniature, Thyroid Gland, Vascular Resistance, Journal Article, Research Support, Non-U.S. Gov't",
author = "J B{\"u}low and J Madsen and L H{\o}jgaard",
year = "1990",
month = may,
language = "English",
volume = "50",
pages = "291--6",
journal = "Scandinavian Journal of Clinical and Laboratory Investigation. Supplement",
issn = "0085-591X",
publisher = "Taylor & Francis",
number = "3",

}

RIS

TY - JOUR

T1 - Reversibility of the effects on local circulation of high lipid concentrations in blood

AU - Bülow, J

AU - Madsen, J

AU - Højgaard, L

PY - 1990/5

Y1 - 1990/5

N2 - Regional perfusion and vascular resistance were examined in different tissues with the radioactive microsphere technique in Göttingen minipigs before, during and after treatment with Intralipid and heparin. This treatment led to an increase in the free fatty acid/albumin molar ratio from 0.39 +/- 0.23 to 3.43 +/- 1.37. Concomitantly a decrease in regional perfusion and an increase in regional vascular resistance was found in skin, adipose tissue, skeletal muscle, kidney, the gastro-intestinal tract, the thyroid and pancreas, while heart and liver showed vasodilatation. The vascular effects were fully reversible when the free fatty acid/albumin molar ratio had normalized. This vascular effect of lipid emulsions has to be considered when patients are treated with parenteral nutrition.

AB - Regional perfusion and vascular resistance were examined in different tissues with the radioactive microsphere technique in Göttingen minipigs before, during and after treatment with Intralipid and heparin. This treatment led to an increase in the free fatty acid/albumin molar ratio from 0.39 +/- 0.23 to 3.43 +/- 1.37. Concomitantly a decrease in regional perfusion and an increase in regional vascular resistance was found in skin, adipose tissue, skeletal muscle, kidney, the gastro-intestinal tract, the thyroid and pancreas, while heart and liver showed vasodilatation. The vascular effects were fully reversible when the free fatty acid/albumin molar ratio had normalized. This vascular effect of lipid emulsions has to be considered when patients are treated with parenteral nutrition.

KW - Adipose Tissue

KW - Animals

KW - Bone and Bones

KW - Coronary Circulation

KW - Digestive System

KW - Fat Emulsions, Intravenous

KW - Fatty Acids, Nonesterified

KW - Female

KW - Heparin

KW - Kidney

KW - Lipids

KW - Liver

KW - Muscles

KW - Pancreas

KW - Serum Albumin

KW - Skin

KW - Swine

KW - Swine, Miniature

KW - Thyroid Gland

KW - Vascular Resistance

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 2353158

VL - 50

SP - 291

EP - 296

JO - Scandinavian Journal of Clinical and Laboratory Investigation. Supplement

JF - Scandinavian Journal of Clinical and Laboratory Investigation. Supplement

SN - 0085-591X

IS - 3

ER -

ID: 165886638