PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)

Research output: Patent

Standard

PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS). / Larsen, Claus Selch (Inventor); Larsen, Susan Weng (Inventor); Thing, Mette Agergaard (Inventor); Kristensen, Jesper Langgaard (Inventor); JENSEN, HENRIK (Inventor); OESTERGAARD, JESPER (Inventor).

Patent No.: WO2013064153. May 10, 2013.

Research output: Patent

Harvard

Larsen, CS, Larsen, SW, Thing, MA, Kristensen, JL, JENSEN, HENRIK & OESTERGAARD, JESPER May. 10 2013, PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS), Patent No. WO2013064153.

APA

Larsen, C. S., Larsen, S. W., Thing, M. A., Kristensen, J. L., JENSEN, HENRIK., & OESTERGAARD, JESPER. (2013). PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS). (Patent No. WO2013064153).

Vancouver

Larsen CS, Larsen SW, Thing MA, Kristensen JL, JENSEN, HENRIK, OESTERGAARD, JESPER, inventors. PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS). WO2013064153. 2013 May 10.

Author

Larsen, Claus Selch (Inventor) ; Larsen, Susan Weng (Inventor) ; Thing, Mette Agergaard (Inventor) ; Kristensen, Jesper Langgaard (Inventor) ; JENSEN, HENRIK (Inventor) ; OESTERGAARD, JESPER (Inventor). / PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS). Patent No.: WO2013064153. May 10, 2013.

Bibtex

@misc{8e5593674e294ec6b3386cac4d105afa,
title = "PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)",
abstract = "The present invention relates to novel depot formulations (prodrugs) comprising an immobility promoting unit linked via an ester to an active pharmaceutical ingredient, i.a. common NSAIDs. The novel depot formulations are suitable for intra-articular injections and are soluble at slightly acidic pH to facilitate ease of injection, and sparingly soluble at physiological pH thereby precipitating at the site of administration. The precipitate will slowly dissolve and the active drug is released from dissolved depot formulation following esterase mediated cleavage of the ester link between the immobility promoting unit and the active pharmaceutical agent.",
author = "Larsen, {Claus Selch} and Larsen, {Susan Weng} and Thing, {Mette Agergaard} and Kristensen, {Jesper Langgaard} and HENRIK JENSEN, and JESPER OESTERGAARD,",
year = "2013",
month = may,
day = "10",
language = "English",
type = "Patent",
note = "WO2013064153; C07D 487/ 04 A I",

}

RIS

TY - PAT

T1 - PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)

AU - Larsen, Claus Selch

AU - Larsen, Susan Weng

AU - Thing, Mette Agergaard

AU - Kristensen, Jesper Langgaard

AU - JENSEN,, HENRIK

AU - OESTERGAARD,, JESPER

PY - 2013/5/10

Y1 - 2013/5/10

N2 - The present invention relates to novel depot formulations (prodrugs) comprising an immobility promoting unit linked via an ester to an active pharmaceutical ingredient, i.a. common NSAIDs. The novel depot formulations are suitable for intra-articular injections and are soluble at slightly acidic pH to facilitate ease of injection, and sparingly soluble at physiological pH thereby precipitating at the site of administration. The precipitate will slowly dissolve and the active drug is released from dissolved depot formulation following esterase mediated cleavage of the ester link between the immobility promoting unit and the active pharmaceutical agent.

AB - The present invention relates to novel depot formulations (prodrugs) comprising an immobility promoting unit linked via an ester to an active pharmaceutical ingredient, i.a. common NSAIDs. The novel depot formulations are suitable for intra-articular injections and are soluble at slightly acidic pH to facilitate ease of injection, and sparingly soluble at physiological pH thereby precipitating at the site of administration. The precipitate will slowly dissolve and the active drug is released from dissolved depot formulation following esterase mediated cleavage of the ester link between the immobility promoting unit and the active pharmaceutical agent.

M3 - Patent

M1 - WO2013064153

ER -

ID: 171123843