Proarrhythmic electrical remodelling is associated with increased beat-to-beat variability of repolarisation

Research output: Contribution to journalJournal articleResearchpeer-review

Acquired long-QT syndrome in combination with increased beat-to-beat variability of repolarisation duration (BVR) is associated with lethal torsades de pointes arrhythmias (TdP) in dogs with remodelled heart after atrioventricular block (AVB). We evaluated the relative contributions of bradycardia and ventricular remodelling to proarrhythmic BVR with and without pharmacological I(Kr) block in order to identify the individual at risk.
Original languageEnglish
JournalCardiovascular Research
Issue number3
Pages (from-to)521-30
Number of pages10
Publication statusPublished - 1 Feb 2007

    Research areas

  • Action Potentials, Acute Disease, Animals, Arrhythmias, Cardiac, Death, Sudden, Cardiac, Dogs, Electrocardiography, Female, Heart Block, Heart Conduction System, Heart Rate, Male, Phenethylamines, Potassium Channel Blockers, Sulfonamides, Torsades de Pointes, Ventricular Remodeling

ID: 45965525