Proarrhythmic electrical remodelling is associated with increased beat-to-beat variability of repolarisation
Research output: Contribution to journal › Journal article › Research › peer-review
Acquired long-QT syndrome in combination with increased beat-to-beat variability of repolarisation duration (BVR) is associated with lethal torsades de pointes arrhythmias (TdP) in dogs with remodelled heart after atrioventricular block (AVB). We evaluated the relative contributions of bradycardia and ventricular remodelling to proarrhythmic BVR with and without pharmacological I(Kr) block in order to identify the individual at risk.
|Number of pages||10|
|Publication status||Published - 1 Feb 2007|
- Action Potentials, Acute Disease, Animals, Arrhythmias, Cardiac, Death, Sudden, Cardiac, Dogs, Electrocardiography, Female, Heart Block, Heart Conduction System, Heart Rate, Male, Phenethylamines, Potassium Channel Blockers, Sulfonamides, Torsades de Pointes, Ventricular Remodeling