Predicting biological networks from genomic data
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Predicting biological networks from genomic data. / Harrington, Eoghan D; Jensen, Lars J; Bork, Peer.
In: F E B S Letters, Vol. 582, No. 8, 2008, p. 1251-8.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Predicting biological networks from genomic data
AU - Harrington, Eoghan D
AU - Jensen, Lars J
AU - Bork, Peer
PY - 2008
Y1 - 2008
N2 - Continuing improvements in DNA sequencing technologies are providing us with vast amounts of genomic data from an ever-widening range of organisms. The resulting challenge for bioinformatics is to interpret this deluge of data and place it back into its biological context. Biological networks provide a conceptual framework with which we can describe part of this context, namely the different interactions that occur between the molecular components of a cell. Here, we review the computational methods available to predict biological networks from genomic sequence data and discuss how they relate to high-throughput experimental methods.
AB - Continuing improvements in DNA sequencing technologies are providing us with vast amounts of genomic data from an ever-widening range of organisms. The resulting challenge for bioinformatics is to interpret this deluge of data and place it back into its biological context. Biological networks provide a conceptual framework with which we can describe part of this context, namely the different interactions that occur between the molecular components of a cell. Here, we review the computational methods available to predict biological networks from genomic sequence data and discuss how they relate to high-throughput experimental methods.
KW - Computational Biology
KW - Genomics
KW - Phylogeny
U2 - 10.1016/j.febslet.2008.02.033
DO - 10.1016/j.febslet.2008.02.033
M3 - Journal article
C2 - 18294967
VL - 582
SP - 1251
EP - 1258
JO - F E B S Letters
JF - F E B S Letters
SN - 0014-5793
IS - 8
ER -
ID: 40749019