Personalized weight loss strategies - the role of macronutrient distribution

Research output: Contribution to journalReviewResearchpeer-review

Standard

Personalized weight loss strategies - the role of macronutrient distribution. / Martinez, J Alfredo; Navas-Carretero, Santiago; Saris, Wim H M; Astrup, Arne.

In: Nature Reviews Endocrinology, Vol. 10, No. 12, 2014, p. 749-760.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Martinez, JA, Navas-Carretero, S, Saris, WHM & Astrup, A 2014, 'Personalized weight loss strategies - the role of macronutrient distribution', Nature Reviews Endocrinology, vol. 10, no. 12, pp. 749-760. https://doi.org/10.1038/nrendo.2014.175

APA

Martinez, J. A., Navas-Carretero, S., Saris, W. H. M., & Astrup, A. (2014). Personalized weight loss strategies - the role of macronutrient distribution. Nature Reviews Endocrinology, 10(12), 749-760. https://doi.org/10.1038/nrendo.2014.175

Vancouver

Martinez JA, Navas-Carretero S, Saris WHM, Astrup A. Personalized weight loss strategies - the role of macronutrient distribution. Nature Reviews Endocrinology. 2014;10(12):749-760. https://doi.org/10.1038/nrendo.2014.175

Author

Martinez, J Alfredo ; Navas-Carretero, Santiago ; Saris, Wim H M ; Astrup, Arne. / Personalized weight loss strategies - the role of macronutrient distribution. In: Nature Reviews Endocrinology. 2014 ; Vol. 10, No. 12. pp. 749-760.

Bibtex

@article{3218c92b670d4ac895690a66b71bdf1c,
title = "Personalized weight loss strategies - the role of macronutrient distribution",
abstract = "A large number of different dietary approaches have been studied in an attempt to achieve healthy, sustainable weight loss among individuals with overweight and obesity. Restriction of energy intake is the primary method of producing a negative energy balance leading to weight loss. However, owing to the different metabolic roles of proteins, carbohydrates and lipids in energy homeostasis, diets of similar overall energy content but with different macronutrient distribution can differentially affect metabolism, appetite and thermogenesis. Evidence increasingly suggests that the fuel values of calories provided by distinct macronutrients should be considered separately, as metabolism of specific molecular components generates differences in energy yield. The causes of variation in individual responses to various diets are currently under debate, and some evidence suggests that differences are associated with specific genotypes. This Review discusses all available systematic reviews and meta-analyses, and summarizes the results of relevant randomized controlled intervention trials assessing the influence of macronutrient composition on weight management. The initial findings of research into personalized nutrition, based on the interactions of macronutrient intake and genetic background and its potential influence on dietary intervention strategies, are also discussed.",
author = "Martinez, {J Alfredo} and Santiago Navas-Carretero and Saris, {Wim H M} and Arne Astrup",
note = "CURIS 2014 NEXS 317",
year = "2014",
doi = "10.1038/nrendo.2014.175",
language = "English",
volume = "10",
pages = "749--760",
journal = "Nature Reviews Endocrinology",
issn = "1759-5029",
publisher = "nature publishing group",
number = "12",

}

RIS

TY - JOUR

T1 - Personalized weight loss strategies - the role of macronutrient distribution

AU - Martinez, J Alfredo

AU - Navas-Carretero, Santiago

AU - Saris, Wim H M

AU - Astrup, Arne

N1 - CURIS 2014 NEXS 317

PY - 2014

Y1 - 2014

N2 - A large number of different dietary approaches have been studied in an attempt to achieve healthy, sustainable weight loss among individuals with overweight and obesity. Restriction of energy intake is the primary method of producing a negative energy balance leading to weight loss. However, owing to the different metabolic roles of proteins, carbohydrates and lipids in energy homeostasis, diets of similar overall energy content but with different macronutrient distribution can differentially affect metabolism, appetite and thermogenesis. Evidence increasingly suggests that the fuel values of calories provided by distinct macronutrients should be considered separately, as metabolism of specific molecular components generates differences in energy yield. The causes of variation in individual responses to various diets are currently under debate, and some evidence suggests that differences are associated with specific genotypes. This Review discusses all available systematic reviews and meta-analyses, and summarizes the results of relevant randomized controlled intervention trials assessing the influence of macronutrient composition on weight management. The initial findings of research into personalized nutrition, based on the interactions of macronutrient intake and genetic background and its potential influence on dietary intervention strategies, are also discussed.

AB - A large number of different dietary approaches have been studied in an attempt to achieve healthy, sustainable weight loss among individuals with overweight and obesity. Restriction of energy intake is the primary method of producing a negative energy balance leading to weight loss. However, owing to the different metabolic roles of proteins, carbohydrates and lipids in energy homeostasis, diets of similar overall energy content but with different macronutrient distribution can differentially affect metabolism, appetite and thermogenesis. Evidence increasingly suggests that the fuel values of calories provided by distinct macronutrients should be considered separately, as metabolism of specific molecular components generates differences in energy yield. The causes of variation in individual responses to various diets are currently under debate, and some evidence suggests that differences are associated with specific genotypes. This Review discusses all available systematic reviews and meta-analyses, and summarizes the results of relevant randomized controlled intervention trials assessing the influence of macronutrient composition on weight management. The initial findings of research into personalized nutrition, based on the interactions of macronutrient intake and genetic background and its potential influence on dietary intervention strategies, are also discussed.

U2 - 10.1038/nrendo.2014.175

DO - 10.1038/nrendo.2014.175

M3 - Review

C2 - 25311395

VL - 10

SP - 749

EP - 760

JO - Nature Reviews Endocrinology

JF - Nature Reviews Endocrinology

SN - 1759-5029

IS - 12

ER -

ID: 126163835