Persistente fluorforbindelser reducerer immunfunktionen
Research output: Contribution to journal › Journal article › peer-review
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Persistente fluorforbindelser reducerer immunfunktionen. / Heilmann, Carsten; Jensen, Lise; Weihe, Pal; Nielsen, Flemming; Knudsen, Lisbeth E.; Budtz-Jørgensen, Esben; Mølbak, Kåre; Grandjean, Philippe.
In: Ugeskrift for Laeger, Vol. 176, No. 7, 30.03.2015, p. 660-663.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Persistente fluorforbindelser reducerer immunfunktionen
AU - Heilmann, Carsten
AU - Jensen, Lise
AU - Weihe, Pal
AU - Nielsen, Flemming
AU - Knudsen, Lisbeth E.
AU - Budtz-Jørgensen, Esben
AU - Mølbak, Kåre
AU - Grandjean, Philippe
PY - 2015/3/30
Y1 - 2015/3/30
N2 - Perfluorinated compounds are highly stable and useful industrial chemicals. Both perfluorooctane sulfonic acid and perfluorooctanoic acid cause immunotoxic effects in animal models at serum concentrations similar to human levels. In children who have undergone routine vaccinations, serum concentrations of these substances are inversely associated with concentrations of antibodies against diphtheria and tetanus. Prevention of such effects will require a decrease of exposure limits by at least 100-fold. Immunotoxicity is not included in routine testing of industrial chemicals but urgently needs attention.
AB - Perfluorinated compounds are highly stable and useful industrial chemicals. Both perfluorooctane sulfonic acid and perfluorooctanoic acid cause immunotoxic effects in animal models at serum concentrations similar to human levels. In children who have undergone routine vaccinations, serum concentrations of these substances are inversely associated with concentrations of antibodies against diphtheria and tetanus. Prevention of such effects will require a decrease of exposure limits by at least 100-fold. Immunotoxicity is not included in routine testing of industrial chemicals but urgently needs attention.
M3 - Tidsskriftartikel
C2 - 25350410
VL - 176
SP - 660
EP - 663
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 7
ER -
ID: 137757241