Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium

Research output: Contribution to journalJournal articlepeer-review

Standard

Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium. / Rosenkrantz, Jesper Tjørnhøj; Aarts, Henk; Abee, Tjakko; Rolfe, Matthew D.; Knudsen, Gitte Maegaard; Nielsen, Maj-Britt; Thomsen, Line Elnif; Zwietering, Marcel H.; Olsen, John Elmerdahl; Pin, Carmen.

In: B M C Microbiology, Vol. 13, 294, 2013.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Rosenkrantz, JT, Aarts, H, Abee, T, Rolfe, MD, Knudsen, GM, Nielsen, M-B, Thomsen, LE, Zwietering, MH, Olsen, JE & Pin, C 2013, 'Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium', B M C Microbiology, vol. 13, 294. https://doi.org/10.1186/1471-2180-13-294

APA

Rosenkrantz, J. T., Aarts, H., Abee, T., Rolfe, M. D., Knudsen, G. M., Nielsen, M-B., Thomsen, L. E., Zwietering, M. H., Olsen, J. E., & Pin, C. (2013). Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium. B M C Microbiology, 13, [294]. https://doi.org/10.1186/1471-2180-13-294

Vancouver

Rosenkrantz JT, Aarts H, Abee T, Rolfe MD, Knudsen GM, Nielsen M-B et al. Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium. B M C Microbiology. 2013;13. 294. https://doi.org/10.1186/1471-2180-13-294

Author

Rosenkrantz, Jesper Tjørnhøj ; Aarts, Henk ; Abee, Tjakko ; Rolfe, Matthew D. ; Knudsen, Gitte Maegaard ; Nielsen, Maj-Britt ; Thomsen, Line Elnif ; Zwietering, Marcel H. ; Olsen, John Elmerdahl ; Pin, Carmen. / Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium. In: B M C Microbiology. 2013 ; Vol. 13.

Bibtex

@article{a5ad8473d15f4adba86beadb59ede72a,
title = "Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium",
abstract = "Salmonella Typhimurium is an important pathogen of human and animals. It shows a broad growth range and survives in harsh conditions. The aim of this study was to analyze transcriptional responses to a number of growth and stress conditions as well as the relationship of metabolic pathways and/or cell functions at the genome-scale-level by network analysis, and further to explore whether highly connected genes (hubs) in these networks were essential for growth, stress adaptation and virulence.",
keywords = "Faculty of Health and Medical Sciences, Salmonella, regulation, metabolism, genom scale network",
author = "Rosenkrantz, {Jesper Tj{\o}rnh{\o}j} and Henk Aarts and Tjakko Abee and Rolfe, {Matthew D.} and Knudsen, {Gitte Maegaard} and Maj-Britt Nielsen and Thomsen, {Line Elnif} and Zwietering, {Marcel H.} and Olsen, {John Elmerdahl} and Carmen Pin",
year = "2013",
doi = "10.1186/1471-2180-13-294",
language = "English",
volume = "13",
journal = "BMC Microbiology",
issn = "1471-2180",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium

AU - Rosenkrantz, Jesper Tjørnhøj

AU - Aarts, Henk

AU - Abee, Tjakko

AU - Rolfe, Matthew D.

AU - Knudsen, Gitte Maegaard

AU - Nielsen, Maj-Britt

AU - Thomsen, Line Elnif

AU - Zwietering, Marcel H.

AU - Olsen, John Elmerdahl

AU - Pin, Carmen

PY - 2013

Y1 - 2013

N2 - Salmonella Typhimurium is an important pathogen of human and animals. It shows a broad growth range and survives in harsh conditions. The aim of this study was to analyze transcriptional responses to a number of growth and stress conditions as well as the relationship of metabolic pathways and/or cell functions at the genome-scale-level by network analysis, and further to explore whether highly connected genes (hubs) in these networks were essential for growth, stress adaptation and virulence.

AB - Salmonella Typhimurium is an important pathogen of human and animals. It shows a broad growth range and survives in harsh conditions. The aim of this study was to analyze transcriptional responses to a number of growth and stress conditions as well as the relationship of metabolic pathways and/or cell functions at the genome-scale-level by network analysis, and further to explore whether highly connected genes (hubs) in these networks were essential for growth, stress adaptation and virulence.

KW - Faculty of Health and Medical Sciences

KW - Salmonella

KW - regulation

KW - metabolism

KW - genom scale network

U2 - 10.1186/1471-2180-13-294

DO - 10.1186/1471-2180-13-294

M3 - Journal article

C2 - 24345035

VL - 13

JO - BMC Microbiology

JF - BMC Microbiology

SN - 1471-2180

M1 - 294

ER -

ID: 92299428