Model of a sub-main transition in phospholipid bilayers
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Model of a sub-main transition in phospholipid bilayers. / Nielsen, Morten; Miao, Ling; Ipsen, John H.; Jørgensen, Kent; Zuckermann, Martin J.; Mouritsen, Ole G.
In: Biochimica et Biophysica Acta - Biomembranes, Vol. 1283, No. 2, 04.09.1996, p. 170-176.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Model of a sub-main transition in phospholipid bilayers
AU - Nielsen, Morten
AU - Miao, Ling
AU - Ipsen, John H.
AU - Jørgensen, Kent
AU - Zuckermann, Martin J.
AU - Mouritsen, Ole G.
PY - 1996/9/4
Y1 - 1996/9/4
N2 - A recently discovered submain phase transition in multi-lamellar bilayers of long-chain saturated diacyl phosphatidylcholines (Jorgensen, K. (1995) Biochim. Biophys. Acta 1240, 111-114) is discussed in terms of a theoretical molecular interaction model using computer simulation techniques. The model interprets the transition to be due to a decoupling of the acyl-chain melting from the melting of the pseudo-two-dimensional crystalline lattice of the P(β') phase. A two-stage melting process is predicted by the calculations suggesting that the sub-main transition involves a lattice melting whereas the acyl-chain melting takes place at a higher temperature at the main transition. The calculated heat contents of the two transitions as well as the chain-length dependence compare favorably with experimental data for multi-lamellar phosphatidylcholine lipid bilayers.
AB - A recently discovered submain phase transition in multi-lamellar bilayers of long-chain saturated diacyl phosphatidylcholines (Jorgensen, K. (1995) Biochim. Biophys. Acta 1240, 111-114) is discussed in terms of a theoretical molecular interaction model using computer simulation techniques. The model interprets the transition to be due to a decoupling of the acyl-chain melting from the melting of the pseudo-two-dimensional crystalline lattice of the P(β') phase. A two-stage melting process is predicted by the calculations suggesting that the sub-main transition involves a lattice melting whereas the acyl-chain melting takes place at a higher temperature at the main transition. The calculated heat contents of the two transitions as well as the chain-length dependence compare favorably with experimental data for multi-lamellar phosphatidylcholine lipid bilayers.
KW - Calorimetry
KW - Chain melting
KW - Lattice melting
KW - Lipid bilayer
KW - Phospholipid
KW - Submain phase transition
KW - Theoretical model
UR - http://www.scopus.com/inward/record.url?scp=0030568836&partnerID=8YFLogxK
U2 - 10.1016/0005-2736(96)00086-7
DO - 10.1016/0005-2736(96)00086-7
M3 - Journal article
C2 - 8809096
AN - SCOPUS:0030568836
VL - 1283
SP - 170
EP - 176
JO - B B A - Biomembranes
JF - B B A - Biomembranes
SN - 0005-2736
IS - 2
ER -
ID: 236887743