Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes: A Nationwide Study of Singleton Deliveries in Denmark

Research output: Contribution to journalJournal articlepeer-review

Standard

Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes : A Nationwide Study of Singleton Deliveries in Denmark. / Nielsen, Karoline Kragelund; Andersen, Gregers Stig; Damm, Peter; Andersen, Anne-Marie Nybo.

In: The Journal of Clinical Endocrinology & Metabolism, Vol. 106, No. 12, 2021, p. e5075–e5087.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Nielsen, KK, Andersen, GS, Damm, P & Andersen, A-MN 2021, 'Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes: A Nationwide Study of Singleton Deliveries in Denmark', The Journal of Clinical Endocrinology & Metabolism, vol. 106, no. 12, pp. e5075–e5087. https://doi.org/10.1210/clinem/dgab528

APA

Nielsen, K. K., Andersen, G. S., Damm, P., & Andersen, A-M. N. (2021). Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes: A Nationwide Study of Singleton Deliveries in Denmark. The Journal of Clinical Endocrinology & Metabolism, 106(12), e5075–e5087. https://doi.org/10.1210/clinem/dgab528

Vancouver

Nielsen KK, Andersen GS, Damm P, Andersen A-MN. Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes: A Nationwide Study of Singleton Deliveries in Denmark. The Journal of Clinical Endocrinology & Metabolism. 2021;106(12):e5075–e5087. https://doi.org/10.1210/clinem/dgab528

Author

Nielsen, Karoline Kragelund ; Andersen, Gregers Stig ; Damm, Peter ; Andersen, Anne-Marie Nybo. / Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes : A Nationwide Study of Singleton Deliveries in Denmark. In: The Journal of Clinical Endocrinology & Metabolism. 2021 ; Vol. 106, No. 12. pp. e5075–e5087.

Bibtex

@article{23460589aaa946e1b7c2a57327a685cb,
title = "Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes: A Nationwide Study of Singleton Deliveries in Denmark",
abstract = "ContextIt remains unclear if migrants have different odds for adverse outcomes associated with gestational diabetes mellitus (GDM).ObjectiveWe investigated if the associations between GDM and adverse pregnancy outcomes are modified by country of origin and examined the odds of these outcomes according to GDM status and country of origin.MethodsData were extracted from a nationwide register-based study of singleton deliveries in Denmark, 2004-2015. We used logistic regression models and tested for interaction.ResultsAmong the 710 413 singleton deliveries, 2.6% had GDM and 14.4% were immigrants. Country of origin modified the association between GDM and pre-eclampsia, large for gestational age (LGA), and small for gestational age (SGA) but not between GDM and planned or emergency cesarean section and preterm delivery. GDM increased the risk of pre-eclampsia among women from Denmark (OR 1.28; 95% CI, 1.18-1.39), Lebanon (OR 3.34; 95% CI, 1.35-8.26), and Morocco (OR 2.28; 95% CI, 1.16-6.88). GDM was associated with increased odds of LGA among women from most countries, particularly women from Sri Lanka (OR 4.20; 95% CI, 2.67-6.61), and was associated with reduced odds of SGA in some countries. Compared with Danish-born women with GDM, the odds of LGA were significantly lower and the odds of SGA higher among women with GDM from India, Lebanon, Pakistan, Iraq, and Somalia.ConclusionsOur study documents that different immigrant groups have higher odds of different GDM-associated adverse pregnancy outcomes and also among countries of origin often grouped together. This highlights the importance of increased awareness to both immigrant background and GDM status in the clinical assessment.",
author = "Nielsen, {Karoline Kragelund} and Andersen, {Gregers Stig} and Peter Damm and Andersen, {Anne-Marie Nybo}",
year = "2021",
doi = "10.1210/clinem/dgab528",
language = "English",
volume = "106",
pages = "e5075–e5087",
journal = "Journal of Clinical Endocrinology and Metabolism",
issn = "0021-972X",
publisher = "Oxford University Press",
number = "12",

}

RIS

TY - JOUR

T1 - Migration, Gestational Diabetes, and Adverse Pregnancy Outcomes

T2 - A Nationwide Study of Singleton Deliveries in Denmark

AU - Nielsen, Karoline Kragelund

AU - Andersen, Gregers Stig

AU - Damm, Peter

AU - Andersen, Anne-Marie Nybo

PY - 2021

Y1 - 2021

N2 - ContextIt remains unclear if migrants have different odds for adverse outcomes associated with gestational diabetes mellitus (GDM).ObjectiveWe investigated if the associations between GDM and adverse pregnancy outcomes are modified by country of origin and examined the odds of these outcomes according to GDM status and country of origin.MethodsData were extracted from a nationwide register-based study of singleton deliveries in Denmark, 2004-2015. We used logistic regression models and tested for interaction.ResultsAmong the 710 413 singleton deliveries, 2.6% had GDM and 14.4% were immigrants. Country of origin modified the association between GDM and pre-eclampsia, large for gestational age (LGA), and small for gestational age (SGA) but not between GDM and planned or emergency cesarean section and preterm delivery. GDM increased the risk of pre-eclampsia among women from Denmark (OR 1.28; 95% CI, 1.18-1.39), Lebanon (OR 3.34; 95% CI, 1.35-8.26), and Morocco (OR 2.28; 95% CI, 1.16-6.88). GDM was associated with increased odds of LGA among women from most countries, particularly women from Sri Lanka (OR 4.20; 95% CI, 2.67-6.61), and was associated with reduced odds of SGA in some countries. Compared with Danish-born women with GDM, the odds of LGA were significantly lower and the odds of SGA higher among women with GDM from India, Lebanon, Pakistan, Iraq, and Somalia.ConclusionsOur study documents that different immigrant groups have higher odds of different GDM-associated adverse pregnancy outcomes and also among countries of origin often grouped together. This highlights the importance of increased awareness to both immigrant background and GDM status in the clinical assessment.

AB - ContextIt remains unclear if migrants have different odds for adverse outcomes associated with gestational diabetes mellitus (GDM).ObjectiveWe investigated if the associations between GDM and adverse pregnancy outcomes are modified by country of origin and examined the odds of these outcomes according to GDM status and country of origin.MethodsData were extracted from a nationwide register-based study of singleton deliveries in Denmark, 2004-2015. We used logistic regression models and tested for interaction.ResultsAmong the 710 413 singleton deliveries, 2.6% had GDM and 14.4% were immigrants. Country of origin modified the association between GDM and pre-eclampsia, large for gestational age (LGA), and small for gestational age (SGA) but not between GDM and planned or emergency cesarean section and preterm delivery. GDM increased the risk of pre-eclampsia among women from Denmark (OR 1.28; 95% CI, 1.18-1.39), Lebanon (OR 3.34; 95% CI, 1.35-8.26), and Morocco (OR 2.28; 95% CI, 1.16-6.88). GDM was associated with increased odds of LGA among women from most countries, particularly women from Sri Lanka (OR 4.20; 95% CI, 2.67-6.61), and was associated with reduced odds of SGA in some countries. Compared with Danish-born women with GDM, the odds of LGA were significantly lower and the odds of SGA higher among women with GDM from India, Lebanon, Pakistan, Iraq, and Somalia.ConclusionsOur study documents that different immigrant groups have higher odds of different GDM-associated adverse pregnancy outcomes and also among countries of origin often grouped together. This highlights the importance of increased awareness to both immigrant background and GDM status in the clinical assessment.

U2 - 10.1210/clinem/dgab528

DO - 10.1210/clinem/dgab528

M3 - Journal article

C2 - 34272865

VL - 106

SP - e5075–e5087

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

SN - 0021-972X

IS - 12

ER -

ID: 286631927