Microbial metabolites as modulators of the infant gut microbiome and host-microbial interactions in early life
Research output: Contribution to journal › Review › Research › peer-review
Documents
- Roager et al_Gut Microbes_2023_Vol 15(1)_e2192151_(Review)
Final published version, 4.04 MB, PDF document
The development of infant gut microbiome is a pivotal process affecting the ecology and function of the microbiome, as well as host health. While the establishment of the infant microbiome has been of interest for decades, the focus on gut microbial metabolism and the resulting small molecules (metabolites) has been rather limited. However, technological and computational advances are now enabling researchers to profile the plethora of metabolites in the infant gut, allowing for improved understanding of how gut microbial-derived metabolites drive microbiome community structuring and host-microbial interactions. Here, we review the current knowledge on development of the infant gut microbiota and metabolism within the first year of life, and discuss how these microbial metabolites are key for enhancing our basic understanding of interactions during the early life developmental window.
Original language | English |
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Article number | 2192151 |
Journal | Gut Microbes |
Volume | 15 |
Issue number | 1 |
Number of pages | 22 |
ISSN | 1949-0976 |
DOIs | |
Publication status | Published - 2023 |
- Metabolites, Metabolomics, Infants, Microbiota, Health, Host, Diet
Research areas
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