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Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort. / Smith, David Hersi; Christensen, Ib Jarle; Jensen, Niels Frank; Markussen, Bo; Rømer, Maria Unni Koefoed; Nygård, Sune Boris; Müller, Sven; Nielsen, Hans Jørgen; Brünner, Nils; Nielsen, Kirsten Vang.
In:
P L o S One, Vol. 8, No. 4, e60613, 2013.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Smith, DH, Christensen, IJ, Jensen, NF
, Markussen, B, Rømer, MUK, Nygård, SB, Müller, S, Nielsen, HJ, Brünner, N & Nielsen, KV 2013, '
Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort',
P L o S One, vol. 8, no. 4, e60613.
https://doi.org/10.1371/journal.pone.0060613APA
Smith, D. H., Christensen, I. J., Jensen, N. F.
, Markussen, B., Rømer, M. U. K., Nygård, S. B., Müller, S., Nielsen, H. J., Brünner, N., & Nielsen, K. V. (2013).
Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort.
P L o S One,
8(4), [e60613].
https://doi.org/10.1371/journal.pone.0060613Vancouver
Smith DH, Christensen IJ, Jensen NF
, Markussen B, Rømer MUK, Nygård SB et al.
Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort.
P L o S One. 2013;8(4). e60613.
https://doi.org/10.1371/journal.pone.0060613Author
Smith, David Hersi ; Christensen, Ib Jarle ; Jensen, Niels Frank ; Markussen, Bo ; Rømer, Maria Unni Koefoed ; Nygård, Sune Boris ; Müller, Sven ; Nielsen, Hans Jørgen ; Brünner, Nils ; Nielsen, Kirsten Vang. / Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort. In: P L o S One. 2013 ; Vol. 8, No. 4.
Bibtex
@article{5e0a11a7e4ae47adb469fecc37fdacd9,
title = "Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort",
abstract = "Topoisomerase I (Top1) is the target of Top1 inhibitor chemotherapy. The TOP1 gene, located at 20q12-q13.1, is frequently detected at elevated copy numbers in colorectal cancer (CRC). The present study explores the mechanism, frequency and prognostic impact of TOP1 gene aberrations in stage III CRC and how these can be detected by fluorescent in situ hybridization (FISH).",
author = "Smith, {David Hersi} and Christensen, {Ib Jarle} and Jensen, {Niels Frank} and Bo Markussen and R{\o}mer, {Maria Unni Koefoed} and Nyg{\aa}rd, {Sune Boris} and Sven M{\"u}ller and Nielsen, {Hans J{\o}rgen} and Nils Br{\"u}nner and Nielsen, {Kirsten Vang}",
year = "2013",
doi = "10.1371/journal.pone.0060613",
language = "English",
volume = "8",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",
}
RIS
TY - JOUR
T1 - Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort
AU - Smith, David Hersi
AU - Christensen, Ib Jarle
AU - Jensen, Niels Frank
AU - Markussen, Bo
AU - Rømer, Maria Unni Koefoed
AU - Nygård, Sune Boris
AU - Müller, Sven
AU - Nielsen, Hans Jørgen
AU - Brünner, Nils
AU - Nielsen, Kirsten Vang
PY - 2013
Y1 - 2013
N2 - Topoisomerase I (Top1) is the target of Top1 inhibitor chemotherapy. The TOP1 gene, located at 20q12-q13.1, is frequently detected at elevated copy numbers in colorectal cancer (CRC). The present study explores the mechanism, frequency and prognostic impact of TOP1 gene aberrations in stage III CRC and how these can be detected by fluorescent in situ hybridization (FISH).
AB - Topoisomerase I (Top1) is the target of Top1 inhibitor chemotherapy. The TOP1 gene, located at 20q12-q13.1, is frequently detected at elevated copy numbers in colorectal cancer (CRC). The present study explores the mechanism, frequency and prognostic impact of TOP1 gene aberrations in stage III CRC and how these can be detected by fluorescent in situ hybridization (FISH).
U2 - 10.1371/journal.pone.0060613
DO - 10.1371/journal.pone.0060613
M3 - Journal article
C2 - 23577133
VL - 8
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 4
M1 - e60613
ER -
