Looking into a Deluded Brain through a Neuroimaging Lens
Research output: Contribution to journal › Journal article › peer-review
Standard
Looking into a Deluded Brain through a Neuroimaging Lens. / Arjmand, Shokouh; Kohlmeier, Kristi A.; Behzadi, Mina; Ilaghi, Mehran; Mazhari, Shahrzad; Shabani, Mohammad.
In: The Neuroscientist, Vol. 27, No. 1, 2021, p. 73-87.Research output: Contribution to journal › Journal article › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Looking into a Deluded Brain through a Neuroimaging Lens
AU - Arjmand, Shokouh
AU - Kohlmeier, Kristi A.
AU - Behzadi, Mina
AU - Ilaghi, Mehran
AU - Mazhari, Shahrzad
AU - Shabani, Mohammad
PY - 2021
Y1 - 2021
N2 - Delusions are irrational, tenacious, and incorrigible false beliefs that are the most common symptom of a range of brain disorders including schizophrenia, Alzheimer's, and Parkinson's disease. In the case of schizophrenia and other primary delusional disorders, their appearance is often how the disorder is first detected and can be sufficient for diagnosis. At this time, not much is known about the brain dysfunctions leading to delusions, and hindering our understanding is that the complexity of the nature of delusions, and their very unique relevance to the human experience has hampered elucidation of their underlying neurobiology using either patients or animal models. Advances in neuroimaging along with improved psychiatric and cognitive modeling offers us a new opportunity to look with more investigative power into the deluded brain. In this article, based on data obtained from neuroimaging studies, we have attempted to draw a picture of the neural networks involved when delusion is present and evaluate whether different manifestations of delusions engage different regions of the brain.
AB - Delusions are irrational, tenacious, and incorrigible false beliefs that are the most common symptom of a range of brain disorders including schizophrenia, Alzheimer's, and Parkinson's disease. In the case of schizophrenia and other primary delusional disorders, their appearance is often how the disorder is first detected and can be sufficient for diagnosis. At this time, not much is known about the brain dysfunctions leading to delusions, and hindering our understanding is that the complexity of the nature of delusions, and their very unique relevance to the human experience has hampered elucidation of their underlying neurobiology using either patients or animal models. Advances in neuroimaging along with improved psychiatric and cognitive modeling offers us a new opportunity to look with more investigative power into the deluded brain. In this article, based on data obtained from neuroimaging studies, we have attempted to draw a picture of the neural networks involved when delusion is present and evaluate whether different manifestations of delusions engage different regions of the brain.
U2 - 10.1177/1073858420936172
DO - 10.1177/1073858420936172
M3 - Journal article
C2 - 32648532
VL - 27
SP - 73
EP - 87
JO - The Neuroscientist
JF - The Neuroscientist
SN - 1073-8584
IS - 1
ER -
ID: 244686950