The karst area in southwest China is, in recent decades, one of the world’s regions with the fastest vegetation growth and increase in aboveground biomass. The improvement in the ecological conditions within this region can, to a large extent, be attributed to ecological protection projects. However, it remains unclear whether the observed increase in vegetation cover could mitigate rocky desertification at large scale. In this study, we utilized information from large field campaigns in the years 2005, 2011, and 2016, supported by satellite imagery interpretation and statistics on ecological protection projects, to explore the impact of restoration efforts on rocky desertification mitigation and vegetation resilience/resistance. The results show that restoration efforts caused a net decrease of 26.14% in areas affected by rocky desertification from 2005 to 2016. The larger the restoration efforts, the stronger the decrease in rocky desertification areas, and also the vulnerability of landscapes towards desertification; the probability of rocky desertification occurring decreased almost linearly with increased restoration efforts. In addition, both vegetation resilience and resistance against climate variations increased with restoration efforts. Restoration efforts were mainly responsible for the recovery of the ecosystem, showing that human impact is the main driver for the reversal of rocky desertification. Our study provides scientific evidence on rocky desertification control being an important step towards a sustainable development of the landscapes of Southwest China.