Is there a risk of active sensitization to PPD by patch testing the general population?
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Is there a risk of active sensitization to PPD by patch testing the general population? / Thyssen, Jacob Pontoppidan; Menné, Torkil; Nielsen, Niels Henrik; Linneberg, Allan.
In: Contact Dermatitis, Vol. 57, No. 2, 08.2007, p. 133-4.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Is there a risk of active sensitization to PPD by patch testing the general population?
AU - Thyssen, Jacob Pontoppidan
AU - Menné, Torkil
AU - Nielsen, Niels Henrik
AU - Linneberg, Allan
PY - 2007/8
Y1 - 2007/8
N2 - Para-phenylenediamine (PPD), a constituent of permanent hair dyes, may cause contact allergy in exposed individuals. It has previously been questioned whether a patch testing with PPD in population-based epidemiological studies is entirely safe. The Glostrup allergy studies patch tested the same cohort twice. In 1990, 567 persons were patch-tested and only one person had a (+) positive reaction to PPD. In 1998, 540 persons were re-invited to a new patch test and 365 (participation rate 68%) were re-tested. There were no positive reactions to PPD. These studies indicate that patch testing with PPD in individuals with no previous positive reactions to PPD or with only one previous positive reaction does not cause active sensitization and can be performed with minimal risk.
AB - Para-phenylenediamine (PPD), a constituent of permanent hair dyes, may cause contact allergy in exposed individuals. It has previously been questioned whether a patch testing with PPD in population-based epidemiological studies is entirely safe. The Glostrup allergy studies patch tested the same cohort twice. In 1990, 567 persons were patch-tested and only one person had a (+) positive reaction to PPD. In 1998, 540 persons were re-invited to a new patch test and 365 (participation rate 68%) were re-tested. There were no positive reactions to PPD. These studies indicate that patch testing with PPD in individuals with no previous positive reactions to PPD or with only one previous positive reaction does not cause active sensitization and can be performed with minimal risk.
KW - Allergens
KW - Coloring Agents
KW - Denmark
KW - Dermatitis, Allergic Contact
KW - Humans
KW - Patch Tests
KW - Phenylenediamines
KW - Risk Factors
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1111/j.1600-0536.2007.01093.x
DO - 10.1111/j.1600-0536.2007.01093.x
M3 - Journal article
C2 - 17627665
VL - 57
SP - 133
EP - 134
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 2
ER -
ID: 173162250