Intake of whole grains is associated with lower risk of myocardial infarction: the Danish Diet, Cancer and Health Cohort

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Intake of whole grains is associated with lower risk of myocardial infarction : the Danish Diet, Cancer and Health Cohort. / Helnæs, Anne; Kyrø, Cecilie; Andersen, Ingelise; Lacoppidan, Sandra; Overvad, Kim; Christensen, Jane; Tjønneland, Anne; Olsen, Anja.

In: The American Journal of Clinical Nutrition, Vol. 103, No. 4, 04.2016, p. 999-1007.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Helnæs, A, Kyrø, C, Andersen, I, Lacoppidan, S, Overvad, K, Christensen, J, Tjønneland, A & Olsen, A 2016, 'Intake of whole grains is associated with lower risk of myocardial infarction: the Danish Diet, Cancer and Health Cohort', The American Journal of Clinical Nutrition, vol. 103, no. 4, pp. 999-1007. https://doi.org/10.3945/ajcn.115.124271

APA

Helnæs, A., Kyrø, C., Andersen, I., Lacoppidan, S., Overvad, K., Christensen, J., Tjønneland, A., & Olsen, A. (2016). Intake of whole grains is associated with lower risk of myocardial infarction: the Danish Diet, Cancer and Health Cohort. The American Journal of Clinical Nutrition, 103(4), 999-1007. https://doi.org/10.3945/ajcn.115.124271

Vancouver

Helnæs A, Kyrø C, Andersen I, Lacoppidan S, Overvad K, Christensen J et al. Intake of whole grains is associated with lower risk of myocardial infarction: the Danish Diet, Cancer and Health Cohort. The American Journal of Clinical Nutrition. 2016 Apr;103(4):999-1007. https://doi.org/10.3945/ajcn.115.124271

Author

Helnæs, Anne ; Kyrø, Cecilie ; Andersen, Ingelise ; Lacoppidan, Sandra ; Overvad, Kim ; Christensen, Jane ; Tjønneland, Anne ; Olsen, Anja. / Intake of whole grains is associated with lower risk of myocardial infarction : the Danish Diet, Cancer and Health Cohort. In: The American Journal of Clinical Nutrition. 2016 ; Vol. 103, No. 4. pp. 999-1007.

Bibtex

@article{4fff8bd519ae47359b0961ca8ab13536,
title = "Intake of whole grains is associated with lower risk of myocardial infarction: the Danish Diet, Cancer and Health Cohort",
abstract = "BACKGROUND: High intake of whole grains has been associated with lower risk of coronary heart disease; however, the research that has been used to evaluate different effects of different whole-grain cereals (e.g., wheat, rye, and oats) has been sparse.OBJECTIVE: We investigated the association between whole-grain intake in terms of total intake and intakes of different cereals and myocardial infarction.DESIGN: This prospective study included 54,871 Danish adults aged 50-64 y, of whom 2329 individuals developed myocardial infarction (13.6 y of follow-up). Detailed information on daily intake of whole-grain products was available from a self-administered food-frequency questionnaire, and intakes of total whole grain and whole-grain species (wheat, rye, and oats) were estimated. The association between intake of whole grains and risk of myocardial infarction was examined with the use of a Cox proportional hazards model adjusted for potential confounders.RESULTS: For both men and women with total whole-grain intake in the highest quartile, lower risks of myocardial infarction were shown [HRs: 0.75 (95% CI: 0.65, 0.86) and 0.73 (95% CI: 0.58, 0.91), respectively] than for individuals with intake in the lowest quartile. When the specific cereal species were considered, rye and oats, but not wheat, were associated with lower myocardial infarction risk in men. No significant associations were seen in women. For total whole-grain products, significantly lower myocardial infarction risks were seen with higher intakes in both men and women. Rye bread (in men and women) and oatmeal (in men) were associated with significantly lower risk of myocardial infarction, whereas no significant association was shown for whole-grain bread, crispbread, and wheat.CONCLUSION: In this study, we provide support for the hypothesis that whole-grain intake is related to lower risk of myocardial infarction and suggest that the cereals rye and oats might especially hold a beneficial effect.",
keywords = "Avena, Denmark, Diet, Female, Food Habits, Humans, Male, Middle Aged, Myocardial Infarction, Neoplasms, Nutrition Assessment, Proportional Hazards Models, Prospective Studies, Risk Factors, Secale, Surveys and Questionnaires, Triticum, Whole Grains, Journal Article",
author = "Anne Heln{\ae}s and Cecilie Kyr{\o} and Ingelise Andersen and Sandra Lacoppidan and Kim Overvad and Jane Christensen and Anne Tj{\o}nneland and Anja Olsen",
note = "{\textcopyright} 2016 American Society for Nutrition.",
year = "2016",
month = apr,
doi = "10.3945/ajcn.115.124271",
language = "English",
volume = "103",
pages = "999--1007",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "4",

}

RIS

TY - JOUR

T1 - Intake of whole grains is associated with lower risk of myocardial infarction

T2 - the Danish Diet, Cancer and Health Cohort

AU - Helnæs, Anne

AU - Kyrø, Cecilie

AU - Andersen, Ingelise

AU - Lacoppidan, Sandra

AU - Overvad, Kim

AU - Christensen, Jane

AU - Tjønneland, Anne

AU - Olsen, Anja

N1 - © 2016 American Society for Nutrition.

PY - 2016/4

Y1 - 2016/4

N2 - BACKGROUND: High intake of whole grains has been associated with lower risk of coronary heart disease; however, the research that has been used to evaluate different effects of different whole-grain cereals (e.g., wheat, rye, and oats) has been sparse.OBJECTIVE: We investigated the association between whole-grain intake in terms of total intake and intakes of different cereals and myocardial infarction.DESIGN: This prospective study included 54,871 Danish adults aged 50-64 y, of whom 2329 individuals developed myocardial infarction (13.6 y of follow-up). Detailed information on daily intake of whole-grain products was available from a self-administered food-frequency questionnaire, and intakes of total whole grain and whole-grain species (wheat, rye, and oats) were estimated. The association between intake of whole grains and risk of myocardial infarction was examined with the use of a Cox proportional hazards model adjusted for potential confounders.RESULTS: For both men and women with total whole-grain intake in the highest quartile, lower risks of myocardial infarction were shown [HRs: 0.75 (95% CI: 0.65, 0.86) and 0.73 (95% CI: 0.58, 0.91), respectively] than for individuals with intake in the lowest quartile. When the specific cereal species were considered, rye and oats, but not wheat, were associated with lower myocardial infarction risk in men. No significant associations were seen in women. For total whole-grain products, significantly lower myocardial infarction risks were seen with higher intakes in both men and women. Rye bread (in men and women) and oatmeal (in men) were associated with significantly lower risk of myocardial infarction, whereas no significant association was shown for whole-grain bread, crispbread, and wheat.CONCLUSION: In this study, we provide support for the hypothesis that whole-grain intake is related to lower risk of myocardial infarction and suggest that the cereals rye and oats might especially hold a beneficial effect.

AB - BACKGROUND: High intake of whole grains has been associated with lower risk of coronary heart disease; however, the research that has been used to evaluate different effects of different whole-grain cereals (e.g., wheat, rye, and oats) has been sparse.OBJECTIVE: We investigated the association between whole-grain intake in terms of total intake and intakes of different cereals and myocardial infarction.DESIGN: This prospective study included 54,871 Danish adults aged 50-64 y, of whom 2329 individuals developed myocardial infarction (13.6 y of follow-up). Detailed information on daily intake of whole-grain products was available from a self-administered food-frequency questionnaire, and intakes of total whole grain and whole-grain species (wheat, rye, and oats) were estimated. The association between intake of whole grains and risk of myocardial infarction was examined with the use of a Cox proportional hazards model adjusted for potential confounders.RESULTS: For both men and women with total whole-grain intake in the highest quartile, lower risks of myocardial infarction were shown [HRs: 0.75 (95% CI: 0.65, 0.86) and 0.73 (95% CI: 0.58, 0.91), respectively] than for individuals with intake in the lowest quartile. When the specific cereal species were considered, rye and oats, but not wheat, were associated with lower myocardial infarction risk in men. No significant associations were seen in women. For total whole-grain products, significantly lower myocardial infarction risks were seen with higher intakes in both men and women. Rye bread (in men and women) and oatmeal (in men) were associated with significantly lower risk of myocardial infarction, whereas no significant association was shown for whole-grain bread, crispbread, and wheat.CONCLUSION: In this study, we provide support for the hypothesis that whole-grain intake is related to lower risk of myocardial infarction and suggest that the cereals rye and oats might especially hold a beneficial effect.

KW - Avena

KW - Denmark

KW - Diet

KW - Female

KW - Food Habits

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Neoplasms

KW - Nutrition Assessment

KW - Proportional Hazards Models

KW - Prospective Studies

KW - Risk Factors

KW - Secale

KW - Surveys and Questionnaires

KW - Triticum

KW - Whole Grains

KW - Journal Article

U2 - 10.3945/ajcn.115.124271

DO - 10.3945/ajcn.115.124271

M3 - Journal article

C2 - 26888710

VL - 103

SP - 999

EP - 1007

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 4

ER -

ID: 169008083