Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study
Research output: Contribution to journal › Journal article › Research › peer-review
Background and purpose: Mortality following infections in dementia has not yet been comprehensively explored. The aim of this cohort study was to investigate the short- and long-term mortality following infections in dementia. Methods: Follow-up was from 1 January 2000 or the 65-year birthday until death, immigration, or 31 December 2015. Exposure was incident dementia and a first infection. The outcome was all-cause mortality. Mortality rate ratios (MRRs) were calculated using Poisson regression in 4 exposure groups (dementia yes/no, infection yes/no) by sex, infection site, and time since infection. Results: 1,496,436 people were followed with 12,739,135 person-years. MRR in dementia/infection was 6.52 (95% confidence interval: 6.43–6.60) and was increased for infections of all sites. Increased mortality was short term (30 days) and long term (10 years). Conclusions: Increased mortality in people with dementia identifies them as a particularly vulnerable group that needs clinical attention.
Original language | English |
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Journal | European Journal of Neurology |
Volume | 28 |
Issue number | 2 |
Pages (from-to) | 411-420 |
Number of pages | 10 |
ISSN | 1351-5101 |
DOIs | |
Publication status | Published - 2021 |
- dementia, epidemiology, infection, mortality, registry-based study
Research areas
ID: 252722642