In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys

Research output: Contribution to journalJournal articlepeer-review

Standard

In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys. / Taghavi, Iman; Andersen, Sofie Bech; Hoyos, Carlos Armando Villagomez; Nielsen, Michael Bachmann; Sorensen, Charlotte Mehlin; Jensen, Jorgen Arendt.

In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 68, No. 10, 2021, p. 3082 - 3093.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Taghavi, I, Andersen, SB, Hoyos, CAV, Nielsen, MB, Sorensen, CM & Jensen, JA 2021, 'In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys', IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 68, no. 10, pp. 3082 - 3093. https://doi.org/10.1109/TUFFC.2021.3086983

APA

Taghavi, I., Andersen, S. B., Hoyos, C. A. V., Nielsen, M. B., Sorensen, C. M., & Jensen, J. A. (2021). In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68(10), 3082 - 3093. https://doi.org/10.1109/TUFFC.2021.3086983

Vancouver

Taghavi I, Andersen SB, Hoyos CAV, Nielsen MB, Sorensen CM, Jensen JA. In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2021;68(10):3082 - 3093. https://doi.org/10.1109/TUFFC.2021.3086983

Author

Taghavi, Iman ; Andersen, Sofie Bech ; Hoyos, Carlos Armando Villagomez ; Nielsen, Michael Bachmann ; Sorensen, Charlotte Mehlin ; Jensen, Jorgen Arendt. / In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys. In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2021 ; Vol. 68, No. 10. pp. 3082 - 3093.

Bibtex

@article{da905f5b83a14252b50e41e66a3451e3,
title = "In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys",
abstract = "Super Resolution (SR) imaging has the potential of visualizing the micro-vasculature down to the 10 μm level, but motion induced by breathing, heartbeats, and muscle contractions are often significantly above this level. The paper therefore introduces a method for estimating tissue motion and compensating for this. The processing pipeline is described and validated using Field II simulations of an artificial kidney. In vivo measurements were conducted using a modified bk5000 research scanner (BK Medical, Herlev, Denmark) with a BK 9009 linear array probe employing a pulse amplitude modulation scheme. The left kidney of ten Sprague-Dawley rats were scanned during open laparotomy. A 1:10 diluted SonoVue contrast agent (Bracco, Milan, Italy) was injected through a jugular vein catheter at 100 μl/min. Motion was estimated using speckle tracking and decomposed into contributions from the heartbeats, breathing and residual motion. The estimated peak motions and their precisions were: Heart: Axial: 7.0 ± 0.55 μm, Lateral: 38 ± 2.5 μm, Breathing Axial: 5 ± 0.29 μm, Lateral: 26 ± 1.3 μm, and Residual: Axial: 30 μm, Lateral: 90 μm. The motion corrected micro-bubble tracks yielded SR images of both bubble density and blood vector velocity. The estimation was, thus, sufficiently precise to correct shifts down to the 10 μm capillary level. Similar results were found in the other kidney measurements with a restoration of resolution for the small vessels demonstrating that motion correction in 2-D can enhance SR imaging quality.",
author = "Iman Taghavi and Andersen, {Sofie Bech} and Hoyos, {Carlos Armando Villagomez} and Nielsen, {Michael Bachmann} and Sorensen, {Charlotte Mehlin} and Jensen, {Jorgen Arendt}",
year = "2021",
doi = "10.1109/TUFFC.2021.3086983",
language = "English",
volume = "68",
pages = "3082 -- 3093",
journal = "I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control",
issn = "0885-3010",
publisher = "Institute of Electrical and Electronics Engineers",
number = "10",

}

RIS

TY - JOUR

T1 - In vivo Motion Correction in Super Resolution Imaging of Rat Kidneys

AU - Taghavi, Iman

AU - Andersen, Sofie Bech

AU - Hoyos, Carlos Armando Villagomez

AU - Nielsen, Michael Bachmann

AU - Sorensen, Charlotte Mehlin

AU - Jensen, Jorgen Arendt

PY - 2021

Y1 - 2021

N2 - Super Resolution (SR) imaging has the potential of visualizing the micro-vasculature down to the 10 μm level, but motion induced by breathing, heartbeats, and muscle contractions are often significantly above this level. The paper therefore introduces a method for estimating tissue motion and compensating for this. The processing pipeline is described and validated using Field II simulations of an artificial kidney. In vivo measurements were conducted using a modified bk5000 research scanner (BK Medical, Herlev, Denmark) with a BK 9009 linear array probe employing a pulse amplitude modulation scheme. The left kidney of ten Sprague-Dawley rats were scanned during open laparotomy. A 1:10 diluted SonoVue contrast agent (Bracco, Milan, Italy) was injected through a jugular vein catheter at 100 μl/min. Motion was estimated using speckle tracking and decomposed into contributions from the heartbeats, breathing and residual motion. The estimated peak motions and their precisions were: Heart: Axial: 7.0 ± 0.55 μm, Lateral: 38 ± 2.5 μm, Breathing Axial: 5 ± 0.29 μm, Lateral: 26 ± 1.3 μm, and Residual: Axial: 30 μm, Lateral: 90 μm. The motion corrected micro-bubble tracks yielded SR images of both bubble density and blood vector velocity. The estimation was, thus, sufficiently precise to correct shifts down to the 10 μm capillary level. Similar results were found in the other kidney measurements with a restoration of resolution for the small vessels demonstrating that motion correction in 2-D can enhance SR imaging quality.

AB - Super Resolution (SR) imaging has the potential of visualizing the micro-vasculature down to the 10 μm level, but motion induced by breathing, heartbeats, and muscle contractions are often significantly above this level. The paper therefore introduces a method for estimating tissue motion and compensating for this. The processing pipeline is described and validated using Field II simulations of an artificial kidney. In vivo measurements were conducted using a modified bk5000 research scanner (BK Medical, Herlev, Denmark) with a BK 9009 linear array probe employing a pulse amplitude modulation scheme. The left kidney of ten Sprague-Dawley rats were scanned during open laparotomy. A 1:10 diluted SonoVue contrast agent (Bracco, Milan, Italy) was injected through a jugular vein catheter at 100 μl/min. Motion was estimated using speckle tracking and decomposed into contributions from the heartbeats, breathing and residual motion. The estimated peak motions and their precisions were: Heart: Axial: 7.0 ± 0.55 μm, Lateral: 38 ± 2.5 μm, Breathing Axial: 5 ± 0.29 μm, Lateral: 26 ± 1.3 μm, and Residual: Axial: 30 μm, Lateral: 90 μm. The motion corrected micro-bubble tracks yielded SR images of both bubble density and blood vector velocity. The estimation was, thus, sufficiently precise to correct shifts down to the 10 μm capillary level. Similar results were found in the other kidney measurements with a restoration of resolution for the small vessels demonstrating that motion correction in 2-D can enhance SR imaging quality.

U2 - 10.1109/TUFFC.2021.3086983

DO - 10.1109/TUFFC.2021.3086983

M3 - Journal article

C2 - 34097608

VL - 68

SP - 3082

EP - 3093

JO - I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control

JF - I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control

SN - 0885-3010

IS - 10

ER -

ID: 272015998