γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket

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γ-Glutamyl-dipeptides, built by condensing the distal carboxylate of L-Glu (or D-Glu) onto a series of differently functionalized amino acids, were prepared and used as tools for rapidly probing the stereoelectronic properties of iGluRs, searching for subtype-selective ligands.
Original languageEnglish
JournalTetrahedron
Volume72
Issue number51
Pages (from-to)8586-8492
Number of pages7
ISSN0040-4020
DOIs
Publication statusPublished - 1 Dec 2016

ID: 168257559